4-Cyanopiperidine
4-Cyanopiperidine
CAS: 4395-98-6
Molecular Formula: C6H10N2
4-Cyanopiperidine - Names and Identifiers
| Name | 4-Cyanopiperidine |
| Synonyms | 4-cyanopiperdine 4-CYANOPIPERIDINE 4-Cyanopiperidine CHEMBRDG-BB 4009819 5-AMINOPHTHALONITRILE 4-Piperidinecarbonitrile Piperidine-4-Carbonitrile PIPERIDINE-4-CARBONITRILE 4-Cyano Piperidine Piperidine-4-Carbonitrile 4-CYANO PIPERIDINE PIPERIDINE-4-CARBONITRILE |
| CAS | 4395-98-6 |
| EINECS | 700-005-4 |
| InChI | InChI=1/C6H10N2/c7-5-6-1-3-8-4-2-6/h6,8H,1-4H2 |
4-Cyanopiperidine - Physico-chemical Properties
| Molecular Formula | C6H10N2 |
| Molar Mass | 110.16 |
| Density | 0.987 g/mL at 25 °C |
| Melting Point | 0°C |
| Boling Point | 0°C |
| Flash Point | 0°C |
| Solubility | Soluble in chloroform. |
| Vapor Presure | 0.082mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless to pale yellow |
| pKa | 9.26±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4755 |
4-Cyanopiperidine - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| UN IDs | 3276 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Harmful |
| Hazard Class | 6.1 |
| Packing Group | III |
4-Cyanopiperidine - Introduction
4-Cyanopiperidine(4-Cyanopiperidine) is an organic compound with the chemical formula C6H10N2 and having one cyano group and one piperidine ring.
It is a colorless to yellow liquid with a pungent odor. It can be dissolved in organic solvents such as ethanol and ether, and can also be dissolved in water, but the solubility is low.
4-Cyanopiperidine has a wide range of applications in the synthesis of organic compounds, pharmaceuticals and other fields. It can be used as pharmaceutical intermediates, such as the synthesis of anti-cancer drugs, antipsychotics, antidepressants and so on. In addition, it can also be used to synthesize chemicals such as spices, pesticides, and dyes.
In the preparation of 4-Cyanopiperidine, a commonly used method is to react 4-chloropiperidine with sodium cyanide to generate the intermediate 4-cyano-1-piperidyl chloride, and then obtain the final product through a hydrolysis reaction 4-Cyanopiperidine.
4-Cyanopiperidine is a toxic compound and should be operated in accordance with safe operating procedures. It has an irritating effect on the eyes, skin and respiratory tract, and may cause redness and burning of the eyes and skin, as well as symptoms such as coughing and difficulty breathing. Wear appropriate protective equipment such as gloves, safety glasses and protective masks during use. During storage and handling, it should be stored in a dry, well-ventilated place, and avoid contact with oxidants, strong acids, strong bases and other substances. If ingested or exposed, seek medical attention immediately.
It is a colorless to yellow liquid with a pungent odor. It can be dissolved in organic solvents such as ethanol and ether, and can also be dissolved in water, but the solubility is low.
4-Cyanopiperidine has a wide range of applications in the synthesis of organic compounds, pharmaceuticals and other fields. It can be used as pharmaceutical intermediates, such as the synthesis of anti-cancer drugs, antipsychotics, antidepressants and so on. In addition, it can also be used to synthesize chemicals such as spices, pesticides, and dyes.
In the preparation of 4-Cyanopiperidine, a commonly used method is to react 4-chloropiperidine with sodium cyanide to generate the intermediate 4-cyano-1-piperidyl chloride, and then obtain the final product through a hydrolysis reaction 4-Cyanopiperidine.
4-Cyanopiperidine is a toxic compound and should be operated in accordance with safe operating procedures. It has an irritating effect on the eyes, skin and respiratory tract, and may cause redness and burning of the eyes and skin, as well as symptoms such as coughing and difficulty breathing. Wear appropriate protective equipment such as gloves, safety glasses and protective masks during use. During storage and handling, it should be stored in a dry, well-ventilated place, and avoid contact with oxidants, strong acids, strong bases and other substances. If ingested or exposed, seek medical attention immediately.
Last Update：2024-04-09 20:52:54
