4-Dimethylaminophenylacetylene - Names and Identifiers
Name | 4'-Dimethylaminophenyl Acetylene
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Synonyms | 1-Ethynyl-4-Dimethylaniline 1-ETHYNYL-4-DIMETHYLANILINE 4-ethynyl-n,n-dimethylaniline 4-Ethynyl-N,N-Dimethylaniline 4-DIMETHYLAMINOPHENYLACETYLENE 4-Dimethylaminophenylacetylene 4'-Dimethylaminophenyl Acetylene 4'-DIMETHYLAMINOPHENYL ACETYLENE 4-ETHYNYL-N,N-DIMETHYLBENZENAMINE (4-ETHYNYL-PHENYL)-DIMETHYL-AMINE N,N-Dimethyl-4-Ethynylbenezeamine (4-Ethynyl-Phenyl)-Dimethyl-Amine N,N-DIMETHYL-4-ETHYNYLBENEZEAMINE 4-Ethynyl-N,N-Dimethylbenzenamine 4-Phenylthiomorpholine 1,1-Dioxide Benzenamine, 4-ethynyl-N,N-dimethyl- (9CI) Benzenamine, 4-Ethynyl-N,N-Dimethyl- (9Ci)
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CAS | 17573-94-3 752235-18-0
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EINECS | 241-675-3 |
InChI | InChI=1/C10H11N/c1-4-9-5-7-10(8-6-9)11(2)3/h1,5-8H,2-3H3 |
4-Dimethylaminophenylacetylene - Physico-chemical Properties
Molecular Formula | C10H11N
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Molar Mass | 145.2 |
Density | 0.98±0.1 g/cm3(Predicted) |
Melting Point | 49-53 °C (lit.) |
Boling Point | 227.9±23.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 0.0754mmHg at 25°C |
Appearance | Solid |
Color | White |
pKa | 3.30±0.12(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.552 |
Physical and Chemical Properties | WGK Germany:3 |
4-Dimethylaminophenylacetylene - Risk and Safety
Hazard Symbols | Xn - Harmful

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Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R42/43 - May cause sensitization by inhalation and skin contact.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
4-Dimethylaminophenylacetylene - Introduction
4 '-Dimethylaminophenyl Acetylene, also known as 1-phenylethynyl-4-dimethylaminobenzene, is an organic compound. The following is a description of the nature, use, preparation and safety information of 4 '-Dimethylaminophenyl Acetylene:
Nature:
-Appearance: Colorless to light yellow liquid
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide
-Melting point: 12-15 degrees Celsius
-Boiling point: 140-150 degrees Celsius
-Density: approx. 0.98g/cm³
Use:
- 4 '-Dimethylaminophenyl Acetylene can be used as a reagent and intermediate in organic synthesis.
-It can participate in a variety of organic reactions, such as Amide synthesis, reduction reaction, C- C coupling reaction and synthesis of aromatic compounds.
-In the field of medicine, it can be used in the production of certain drugs, such as the synthesis of anti-cancer drugs.
Method:
-Under normal circumstances, 4 '-Dimethylaminophenyl Acetylene can be prepared by organic synthesis.
-A common preparation method is to first synthesize p-nitrobenzaldehyde, and then perform a dealdehyde reaction in the presence of amine to obtain 4 '-Dimethylaminophenyl Acetylene.
Safety Information:
- 4 '-Dimethylaminophenyl Acetylene is a chemical and should be used safely.
-It may be irritating to the skin, eyes and respiratory system. Avoid direct contact with skin and eyes when touching, and ensure good ventilation.
-Wear appropriate personal protective equipment such as chemical protective gloves, goggles and protective masks when used.
-Use, store and handle the chemical in accordance with proper laboratory practices and safety practices, and keep it away from ignition and other flammable substances.
Last Update:2024-04-09 02:00:43