4-Ethyl-3-bromopyridine

4-Ethyl-3-bromopyridine - Names and Identifiers

Name	3-Bromo-4-ethyl-pyridine
Synonyms	4-Ethyl-3-Bromopyridine 4-Ethyl-3-bromopyridine 3-Bromo-4-ethyl-pyridine Pyridine, 3-bromo-4-ethyl- Pyridine, 3-bromo-4-ethyl- (9CI)
CAS	38749-76-7
InChI	InChI=1/C7H8BrN/c1-2-6-3-4-9-5-7(6)8/h3-5H,2H2,1H3

4-Ethyl-3-bromopyridine - Physico-chemical Properties

Molecular Formula	C7H8BrN
Molar Mass	186.05
Density	1.413±0.06 g/cm3(Predicted)
Boling Point	216.7±20.0 °C(Predicted)
Flash Point	84.8°C
Vapor Presure	0.203mmHg at 25°C
pKa	3.68±0.18(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.544

4-Ethyl-3-bromopyridine - Introduction

3-Bromo-4-ethyl-pyridine is an organic compound with the chemical formula C8H10BrN. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless liquid or solid.
-Molecular weight: 207.08g/mol.
-Melting point:-17°C.
-Boiling point: 206-208°C.
-Density: 1.444g/cm³.
-Solubility: Soluble in organic solvents, slightly soluble in water.

Use:
- 3-Bromo-4-ethyl-pyridine is commonly used as an intermediate in organic synthesis.
-It can be used to prepare optically active molecules and pharmaceutical compounds.
-The compound can also be used as a catalyst, a complexing agent and a halogenating agent.

Preparation Method:
The preparation method of 3-Bromo-4-ethyl-pyridine can be carried out by the following steps:
1. 3-bromopyridine is reacted with vinyl magnesium halide (such as ethyl magnesium bromide) in an inert solvent (such as dimethylformamide).
2. The reaction mixture was cooled and acidified to give the desired product.

Safety Information:
-3-Bromo-4-ethyle-pyridine is a flammable liquid, need to pay attention to fire prevention measures.
-When using or operating, it is recommended to wear protective glasses and gloves to avoid contact with skin and eyes.
-The compound may be harmful to the environment, and care should be taken to prevent it from entering water or soil.
-Appropriate safety practices should be followed during storage and handling. Observe local laws and regulations during waste disposal.

Last Update：2024-04-09 15:17:57