4-FLUORO-1-IODO-2-NITROBENZENE

4-FLUORO-1-IODO-2-NITROBENZENE - Names and Identifiers

Name	4-Fluoro-1-iodo-2-nitrobenzene
Synonyms	5-FLUORO-2-IODONITROBENZENE 2-IODO-5-FLUORONITROBENZENE 4-Fluoro-2-Nitroiodobenzene 2-Iodo-5-fluoronitrobenzene 5-fluoro-2-iodonitrobenzene 4-Fluoro-1-iodo-2-nitrobenzene 4-FLUORO-1-IODO-2-NITROBENZENE 1-FLUORO-4-IODO-3-NITROBENZENE
CAS	364-77-2
EINECS	642-661-3
InChI	InChI=1/C6H5FN2O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,8H2

4-FLUORO-1-IODO-2-NITROBENZENE - Physico-chemical Properties

Molecular Formula	C6H3FINO2
Molar Mass	267
Density	2.093
Boling Point	110°C 4mm
Flash Point	110°C/4mm
Vapor Presure	0.00155mmHg at 25°C
Appearance	powder to lump
Color	Light yellow to Yellow to Orange
BRN	3253380
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Sensitive	Light Sensitive
Refractive Index	1.615
MDL	MFCD00153169

4-FLUORO-1-IODO-2-NITROBENZENE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
HS Code	29049090
Hazard Note	Irritant
Hazard Class	IRRITANT, LIGHT SENS

4-FLUORO-1-IODO-2-NITROBENZENE - Introduction

It is an organic compound with a chemical formula of C6H3FINO2 and a molecular weight of 253.01g/mol. The following is a description of the properties, uses, preparation and safety information of this compound:

Nature:
-Appearance: It is a solid, commonly yellow crystal.
-Melting point: about 80-83 ℃.
-Boiling point: about 288 ℃ (decomposition).
-Density: Approximately 2.12 g/mL(20°C).
-Solubility: Soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane.
-Stability: Stable at room temperature, but avoid prolonged exposure to light and high temperature.

Use:
-is often used as an intermediate in organic synthesis.
-It can be used to synthesize other organic compounds, such as drugs and pesticides.

Preparation Method:
The preparation method can be achieved by iodination reaction and electrophilic substitution reaction:
1. First, 1,3-difluorobenzene (4-fluorophenyl fluoride) is reacted with a nucleophile sodium iodide (NaI) in an organic solvent to obtain 4-fluoro-1-iodobenzene (4-fluoro-1-iodobenzene).
2. Then, 4-fluoro-1-iodobenzene is reacted with nitrating reagent nitric acid (HNO3) under appropriate conditions to obtain fluorobenzene.

Safety Information:
-is an organic compound and care should be taken to comply with relevant safety procedures and procedures.
-Wear appropriate protective equipment such as chemical goggles, gloves and lab coats when used.
-Avoid inhalation, ingestion or contact with skin, eyes and mucous membranes.
-If you come into contact with this compound, immediately flush the affected area with plenty of water and seek medical help.

Last Update：2024-04-09 21:01:54