4-Fluoro-1-acetonaphthone

4-Fluoro-1-acetonaphthone - Names and Identifiers

Name	4'-fluoro-1'-acetonaphthone
Synonyms	4-Fluoroacetonaphthone 4-FLUORO-1-ACETONAPHTHONE 4-Fluoro-1-acetonaphthone 4'-fluoro-1'-acetonaphthone 4'-FLUORO-1'-ACETONAPHTHONE 1-(4-fluoro-1-naphthyl)ethan-1-one 1-(4-Fluoro-1-naphthalenyl)ethanone 1-(4-fluoronaphthalen-1-yl)ethanone
CAS	316-68-7
EINECS	206-261-9
InChI	InChI=1/C12H9FO/c1-8(14)9-6-7-12(13)11-5-3-2-4-10(9)11/h2-7H,1H3

4-Fluoro-1-acetonaphthone - Physico-chemical Properties

Molecular Formula	C12H9FO
Molar Mass	188.2
Density	1.203g/mLat 25°C(lit.)
Melting Point	33-35°C(lit.)
Boling Point	167°C17mm Hg(lit.)
Flash Point	>230°F
Vapor Presure	0.00162mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	n20/D 1.608(lit.)
MDL	MFCD00134475

4-Fluoro-1-acetonaphthone - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
Hazard Note	Irritant

4-Fluoro-1-acetonaphthone - Introduction

4 '-fluoro-1'-acetonaphthone is an organic compound with the chemical formula C12H9FO. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 4 '-fluoro-1'-acetonaphthone is a white crystalline solid with a special aroma.
-Melting point: Its melting point is 55-57°C.
-Boiling point: Its boiling point is 247-250 ℃.
-Solubility: 4 '-fluoro-1'-acetonaphthone is soluble in organic solvents such as ethanol, benzene and dichloromethane.

Use:
- 4 '-fluoro-1'-acetonaphthone is mainly used as an important intermediate in organic synthesis and can be used to synthesize other organic compounds.
-It can also be used as fluorescent dyes, pharmaceutical intermediates and raw materials for dyes and fragrances.

Method:
- 4 '-fluoro-1'-acetonaphthone can be prepared by fluorination reaction. A common method is to use a fluorinating reagent such as hydrofluoric acid or hydrofluoric acid gas to react with 1-naphthalene ethyl ketone under alkaline conditions to introduce fluorine atoms into the molecular structure of 1-naphthalene ethyl ketone, thus, the fluoro derivative thereof was prepared.

Safety Information:
-There are limited data and studies on the toxicity and danger of 4 '-fluoro-1'-acetonaphthone. Therefore, the use should follow the general laboratory safety practice.
-It is an irritant substance that may cause irritation or allergic reactions when in contact with the skin, eyes or respiratory system. Therefore, appropriate personal protective equipment, such as laboratory gloves, safety glasses and protective masks, should be used during operation.
-During storage, 4 '-fluoro-1'-acetonaphthone should be placed in a sealed container and kept away from fire and oxidizing agents. Storage conditions should be at room temperature or low temperature environment.

Please note that the above information is for reference only. When using and handling chemicals, strictly follow laboratory safety practices and refer to specific chemical safety data sheets (MSDS) and relevant literature.

Last Update：2024-04-09 20:48:19