Name | 4-Fluoro-1H-pyrazole |
Synonyms | 4-Fluoro-1H-pyrazole 1H-Pyrazole, 4-fluoro- 4-Fluoro-1H-pyrazole fandachem 4-Fluoro-1H-pyrazole4-Fluoro-1H-pyrazole |
CAS | 35277-02-2 |
Molecular Formula | C3H3FN2 |
Molar Mass | 86.0677 |
Density | 1.320 |
Melting Point | 38-40 °C |
Boling Point | 193℃ |
Flash Point | 70℃ |
pKa | 13.66±0.50(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Use | Use 4-fluoro-1h-pyrazole as heterocyclic organic compounds, can be used as organic intermediates. |
Raw Materials | (2Z)-3-(Diethylamino)-2-fluoroprop-2-enal Silane, (fluoroethynyl)trimethyl- (9CI) 2-Propenal, 3-(dimethylamino)-2-fluoro- 4-fluoro-5-(tributylstannyl)-1H-pyrazole 1,1-DIFLUOROETHYLENE |
The preparation of 4-fluoro-1H-pyrazole is first hydrolyzed from ethyl 2-fluoroacetate as a raw material to obtain sodium 2-fluoroacetate, and then reacted with DMF to obtain (Z)-3-(dimethylamino)-2-fluoroacrolein, and finally obtained by ring-closing with dihydrohydrazine hydrochloride.