4-Fluoro-2,3-dihydro-isoindol-1-one

4-Fluoro-2,3-dihydro-isoindol-1-one - Names and Identifiers

Name	1H-Isoindol-1-one, 4-fluoro-2,3-dihydro-
Synonyms	4-fluoroisoindolin-1-one 4-Fluoro-2,3-dihydroisoindol-1-one 4-Fluoro-2,3-dihydro-isoindol-1-one 4-Fluoro-2,3-dihydro-1H-isoindol-1-one 1H-Isoindol-1-one,4-fluoro-2,3-dihydro- 1H-Isoindol-1-one, 4-fluoro-2,3-dihydro- 1H-Isoindol-1-one,4-fluoro-2,3-dihydro-(9CI)
CAS	366452-96-2

4-Fluoro-2,3-dihydro-isoindol-1-one - Physico-chemical Properties

Molecular Formula	C8H6FNO
Molar Mass	151.14

4-Fluoro-2,3-dihydro-isoindol-1-one - Introduction

1H-Isoindol-1-one, 4-fluoro-2,3-dihydro-, chemical formula C8H5FO, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 1H-Isoindol-1-one, 4-fluoro-2,3-dihydro-as a white crystalline solid.
-Solubility: It dissolves in organic solvents such as ethanol, dimethylformamide and dichloromethane, but is almost insoluble in water.
-Melting point: Its melting point is about 190-195 degrees Celsius.

Use:
- 1H-Isoindol-1-one, 4-fluoro-2,3-dihydro-can be used as drug intermediates and have certain applications in the field of medicine.
-It can also be used in organic synthesis reactions as a starting material for the synthesis of other organic compounds.

Preparation Method:
- 1H-Isoindol-1-one, 4-fluoro-2,3-dihydro-has many preparation methods, one of which is obtained by fluorination, reduction and ketonization of nitroindole.
-The specific steps include reacting nitroindole with hydrofluoric acid, reducing it with ferrous iron to obtain fluoroindole, and finally reacting fluoroindole with ketone reagent to obtain 1H-Isoindol-1-one, 4-fluoro-2,3-dihydro-.

Safety Information:
- 1H-Isoindol-1-one, 4-fluoro-2,3-dihydro-is generally relatively safe under correct use and storage.
-However, as a chemical, users should follow the relevant safety procedures, avoid contact with skin and eyes, and do not breathe its dust or gas.
-Keep away from open flames and high temperatures during use or storage, and avoid contact with oxidants.
-When handling this compound, care should be taken to use appropriate protective measures, such as gloves, glasses and protective clothing, to protect personal safety.

Last Update：2024-04-09 02:00:45