4-Fluoro-2-hydroxyacetophenone

4-Fluoro-2-hydroxyacetophenone - Names and Identifiers

Name	4-Fluoro-2-hydroxyacetophenone
Synonyms	4-FLUORO-2-HYDROXYACETOPHE uoro-2'-hydroxyacetophenone 4-Fluoro-2-hydroxyacetophenone 4-FLUORO-2-HYDROXYACETOPHENONE 4'-Fluoro-2'-hydroxyacetophenone 4'-FLUORO-2'-HYDROXYACETOPHENONE 4'-fluoro-2'-hydroxyacetophenone 4'-fluoro-2'-hydroxyacetophenone,1-(4-fluoro-2-hydroxyphenyl)ethanone
CAS	1481-27-2
InChI	InChI=1/C9H7FO/c10-7-3-1-6-2-4-9(11)8(6)5-7/h1,3,5H,2,4H2
InChIKey	HLTBTUXAMVOKIH-UHFFFAOYSA-N

4-Fluoro-2-hydroxyacetophenone - Physico-chemical Properties

Molecular Formula	C8H7FO2
Molar Mass	154.14
Density	1.1850 (estimate)
Melting Point	32-34°C
Boling Point	65°C 2mm
Flash Point	98°C
Vapor Presure	0.0525mmHg at 25°C
Appearance	White solid
BRN	2249799
pKa	9.17±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.559
MDL	MFCD00143203

4-Fluoro-2-hydroxyacetophenone - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29147000
Hazard Class	IRRITANT

4-Fluoro-2-hydroxyacetophenone - Introduction

The chemical formula C8H7FO2 is an organic compound. The following is a brief description of its nature, use, preparation and safety information:

Nature:
-Appearance: A colorless to pale yellow liquid.
-Solubility: Soluble in alcohol and ether, insoluble in water.
-Melting point: About -15 ° C.
-Boiling point: About 209 ° C.
-Density: about 1.24g/cm³.

Use:
It is often used as an intermediate in organic synthesis and has important synthetic application value. It can be used to prepare organic compounds such as pharmaceuticals, pesticides, dyes and fragrances. Its hydroxyl group and fluorine atom make it have strong activity and selectivity in organic synthesis.

Method:
The preparation of fluorobenzoic acid is usually obtained by acid hydrolysis reaction of fluorobenzoic acid ester. The specific preparation method may vary depending on the experimental conditions.

Safety Information:
-is generally considered to be a low-toxic substance in organic compounds.
-Its vapor can cause irritation to the eyes and skin, so you should avoid contact during operation.
-During use and storage, avoid contact with oxidants and strong acids to avoid dangerous reactions.
-During handling, transportation and storage, strict compliance with relevant safety practices is required.

Last Update：2024-04-09 20:49:11