4-HYDROXYPYRIDINE
4-HYDROXYPYRIDINE
CAS: 108-96-3
Molecular Formula: C5H5NO
4-HYDROXYPYRIDINE - Names and Identifiers
| Name | 4-HYDROXYPYRIDINE |
| Synonyms | 4HPY G-PYRIDONE 4-PYRIDONE 4-(1H)-PYRIDONE 4(1h)-pyridinone 4-HYDROXYPYRIDINE pyridin-4(3H)-one TIMTEC-BB SBB005800 |
| CAS | 108-96-3 |
| EINECS | 203-633-2 |
4-HYDROXYPYRIDINE - Physico-chemical Properties
| Molecular Formula | C5H5NO |
| Molar Mass | 95.1 |
| Density | 1.1418 (rough estimate) |
| Melting Point | 150-151 °C(lit.) |
| Boling Point | 230-235 °C12 mm Hg(lit.) |
| Flash Point | 212°C |
| pKa | 10.87±0.69(Predicted) |
| PH | 7.0 (50g/l, H2O, 20°C) |
| Storage Condition | Store below +30°C. |
| Refractive Index | 1.5939 (estimate) |
| Physical and Chemical Properties | EPA Chemical Information 4(1H)-Pyridinone (108-96-3) |
| Use | Use pyridone is a kind of organic compound framework with important biological activity and medicinal value, which is used to synthesize diuretic drug torasemide or other drug intermediates; therefore, it is of great research significance and application value to develop simple and efficient methods to realize the functionalization of pyridone; |
4-HYDROXYPYRIDINE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | UU7701450 |
| FLUKA BRAND F CODES | 3-8-10 |
| HS Code | 2933 39 99 |
| Toxicity | LD50 orally in Rabbit: 4600 mg/kg |
4-HYDROXYPYRIDINE - Upstream Downstream Industry
4-HYDROXYPYRIDINE - Security information
| auto-ignition temperature | 515 °C |
Last Update：2024-04-10 22:29:15
4-HYDROXYPYRIDINE - Overview
pyridone is an intermediate in the process of producing 3,5,6,-trichloropyridine sodium. It is an important chemical raw material and is mainly used in the production of pesticide chlorpyrifos and Class A chlorpyrifos. It is a pesticide intermediate. At present, the most valuable method for preparing pyridone is the trichloroacetyl chloride method. In this method, under the action of a catalyst, trichloroacetyl chloride is reacted with acrylonitrile, and the obtained product is closed-loop, crystallized, and centrifuged to obtain pyridone. One of the main raw materials of the method is trichloroacetyl chloride, and the final yield of pyridone is measured by trichloroacetyl chloride, because its price is the most expensive among the main raw materials. The existing methods of using trichloroacetyl chloride method to prepare pyridone are all synthesized from trichloroacetyl chloride as raw material, which often requires outsourcing of trichloroacetyl chloride in actual large-scale production, which not only consumes manpower and material resources, but also It also increases freight and storage costs, which virtually increases the production cost of pyridone and reduces the competitiveness of enterprises.
Last Update：2024-04-09 21:04:16
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