4-Hydroxy-6-methoxyquinoline

4-Hydroxy-6-methoxyquinoline - Names and Identifiers

Name	4-Hydroxy-6-methoxyquinoline
Synonyms	Nsc76096 6-METHOXYQUINOLIN-4-OL 6-METHOXY-4-QUINOLINOL 6-METHOXYQUINOLIN-4(1H)-ONE 6-METHOXY-4(1H)-QUINOLINONE 6-methoxyquinolin-4(1H)-one 6-METHOXY-4-HYDROXYQUINOLINE 4-HYDROXY-6-METHOXYQUINOLINE 6-Methoxy-4-hydroxyquinoline 4-Hydroxy-6-methoxyquinoline 6-Methoxy-4(1H)-quinolinone([13788-72-2])
CAS	23432-39-5
EINECS	803-465-5
InChI	InChI=1/C10H9NO2/c1-13-7-2-3-9-8(6-7)10(12)4-5-11-9/h2-6H,1H3,(H,11,12)

4-Hydroxy-6-methoxyquinoline - Physico-chemical Properties

Molecular Formula	C10H9NO2
Molar Mass	175.18
Density	1.258±0.06 g/cm3(Predicted)
Melting Point	225-244 °C(Solv: water (7732-18-5))
Boling Point	351.8±22.0 °C(Predicted)
Flash Point	148.2°C
Vapor Presure	0.000296mmHg at 25°C
pKa	4.40±0.40(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.573

4-Hydroxy-6-methoxyquinoline - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3

4-Hydroxy-6-methoxyquinoline - Introduction

It is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Solid is a white or light yellow crystal.
-Solubility: Soluble in common organic solvents.
-Melting point: Its melting point is about 185-186 ° C.

Use:
-Antibacterial activity: It has certain antibacterial activity and can be used as an intermediate for antibacterial agents or antimicrobial drugs.
-Drug research: The compound is used as one of the components of antimalarial drugs in drug research, and can be used to synthesize drugs such as chloroquine.

Method:
The preparation method of 2-bromo-3-methoxyquinoline can be obtained by reacting 2-amino-3-methoxynaphthalene with bromoacetic acid, the target product is then obtained by lithium aluminum hydride reduction.

Safety Information: In general, the safety of the human body is better, but appropriate safety measures are still needed, such as wearing gloves and ventilation.
-This compound may cause irritation when in contact with eyes, skin and inhalation and contact with these areas should be avoided.
-in use should pay attention to avoid eating.
-When storing and handling, it should be separated from flammable materials and properly sealed.

Please note: The information provided above is for reference only. If you need to use this compound, please follow the corresponding safety procedures and instructions for use.

Last Update：2024-04-09 15:17:56