4-Hydroxy-6-methoxyquinoline-3-carbonitrile

4-Hydroxy-6-methoxyquinoline-3-carbonitrile - Names and Identifiers

Name	4-Hydroxy-6-methoxyquinoline-3-carbonitrile
Synonyms	6-methoxy-4-oxo-1H-quinoline-3-carbonitrile 4-Hydroxy-6-methoxyquinoline-3-carbonitrile 3-Quinolinecarbonitrile, 4-hydroxy-6-Methoxy- 6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile
CAS	13669-61-9
InChI	InChI=1/C11H8N2O2/c1-15-8-2-3-10-9(4-8)11(14)7(5-12)6-13-10/h2-4,6H,1H3,(H,13,14)

4-Hydroxy-6-methoxyquinoline-3-carbonitrile - Physico-chemical Properties

Molecular Formula	C11H8N2O2
Molar Mass	200.19
Density	1.36±0.1 g/cm3(Predicted)
Boling Point	422.1±45.0 °C(Predicted)
Flash Point	169.1°C
Vapor Presure	3.01E-05mmHg at 25°C
pKa	1.21±0.50(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.62

4-Hydroxy-6-methoxyquinoline-3-carbonitrile - Introduction

3-Cyano-4-hydroxy-6-methoxyquinoline is an organic compound with the chemical formula C10H8N2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3-Cyano-4-hydroxy-6-methoxyquinoline is a white to off-white crystalline powder.
-Solubility: insoluble in water, but can be dissolved in some organic solvents, such as ethanol, benzene and dichloromethane.
-Melting point: about 203-205°C.

Use:
-3-Cyano-4-hydroxy-6-methoxyquinoline is widely used in the field of medicine. As an organic synthesis intermediate, it can be used to synthesize a series of compounds with biological activity.
-It has important application value in the synthesis of drugs, pesticides and dyes.

Preparation Method:
The preparation of-3-cyano-4-hydroxy-6-methoxyquinoline is generally achieved by chemical synthesis methods. A commonly used synthesis method is to react p-methoxyphenol with cyanomethylene chloride to obtain 3-cyano-4-methoxyphenol, which is then condensed with 2-amino-3-hydroxypyridine to form the target product.

Safety Information:
-3-cyano-4-hydroxy-6-methoxyquinoline has good stability under general conditions of use, but contact with strong oxidants should be avoided.
-During use, you should wear appropriate protective measures, such as gloves and goggles, to prevent contact with skin and eyes.
-Storage should be placed in a dry, cool and well-ventilated place, away from fire and high temperature.
-If ingestion, inhalation or skin contact occurs, seek medical attention immediately and bring the compound's label or safety data sheet.

Last Update：2024-04-09 02:00:42