4-Hydroxy-a,a,a-trifluoro-m-tolualdehyde

4-Hydroxy-a,a,a-trifluoro-m-tolualdehyde - Names and Identifiers

Name	4-Hydroxy-3-(trifluoromethyl)benzaldehyde
Synonyms	VHR DQ CXFFF [WLN] 4-Hydroxy-3-trifluoromethyl-benzaldehyde 4-Hydroxy-a,a,a-trifluoro-m-tolualdehyde 4-HYDROXY-3-(TRIFLUOROMETHYL)BENZALDEHYDE 4-Hydroxy-3-(trifluoromethyl)benzaldehyde Benzaldehyde, 4-hydroxy-3-(trifluoromethyl)- 4-Formyl-2-(trifluoromethyl)phenol, 5-Formyl-2-hydroxybenzotrifluoride
CAS	220227-98-5
InChI	InChI=1/C8H5F3O2/c9-8(10,11)6-3-5(4-12)1-2-7(6)13/h1-4,13H

4-Hydroxy-a,a,a-trifluoro-m-tolualdehyde - Physico-chemical Properties

Molecular Formula	C8H5F3O2
Molar Mass	190.12
Density	1.429±0.06 g/cm3(Predicted)
Melting Point	159-163°C
Boling Point	224.0±35.0 °C(Predicted)
Flash Point	89.3°C
Vapor Presure	0.0626mmHg at 25°C
Appearance	Crystalline powder
pKa	5.79±0.43(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive
Refractive Index	1.511
MDL	MFCD01091006

4-Hydroxy-a,a,a-trifluoro-m-tolualdehyde - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3
Hazard Note	Irritant

4-Hydroxy-a,a,a-trifluoro-m-tolualdehyde - Introduction

4-Hydroxy-3-(trifluoromethyl)benzaldehyde is an organic compound with the chemical formula C8H5F3O2. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
-Appearance: Colorless solid
-Solubility: Soluble in alcohol and ether, slightly soluble in water
-Melting point: About 75-76 ° C
-Boiling point: About 169-170 ° C

Use:
-In organic synthesis, 4-Hydroxy-3-(trifluoromethyl)benzaldehyde is often used as an intermediate for the synthesis of other compounds.
-It is also used in pharmaceutical research, such as the synthesis of some compounds containing nitrogen heterocycles.

Method:
-4-Hydroxy-3-(trifluoromethyl)benzaldehyde can be prepared by esterification of trifluoroformic acid and p-hydroxybenzaldehyde. The specific reaction conditions can be confirmed according to the protocol implemented by the specific laboratory.

Safety Information:
- 4-Hydroxy-3-(trifluoromethyl)benzaldehyde may be irritating to the eyes and skin, so care should be taken to avoid contact during operation.
-Should be stored in a sealed container at room temperature, away from fire and oxidizing agents.
-Use in accordance with appropriate laboratory safety practices and wear protective gloves and glasses. Operate in areas where toxic substances are treated.
-For detailed safety information, please refer to the relevant safety data form for the compound or consult the chemical supplier.

Last Update：2024-04-09 20:49:11