4-Hydroxyphenylethylamine
2-(4-Hydroxyphenyl)ethylamine
CAS: 51-67-2
Molecular Formula: C8H11NO
4-Hydroxyphenylethylamine - Names and Identifiers
4-Hydroxyphenylethylamine - Physico-chemical Properties
| Molecular Formula | C8H11NO |
| Molar Mass | 137.18 |
| Density | 1.0630 (rough estimate) |
| Melting Point | 160-162°C(lit.) |
| Boling Point | 175-181°C8mm Hg(lit.) |
| Flash Point | 165°C |
| JECFA Number | 1590 |
| Water Solubility | 1g/95mL (15 ºC) |
| Solubility | Soluble in ethanol, slightly soluble in water, benzene, xylene. |
| Vapor Presure | 0.000123mmHg at 25°C |
| Appearance | Crystal powder |
| Color | Clear yellow to orange to slightly brown, may darken on storage |
| Merck | 14,9835 |
| BRN | 1099914 |
| pKa | 9.74(at 25℃) |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong acids, strong oxidizing agents. |
| Sensitive | Sensitive to air |
| Refractive Index | 1.5849 (estimate) |
| MDL | MFCD00008193 |
| Physical and Chemical Properties | Melting point 155-163°C boiling point 175-181°C (8 mmHg) water-soluble 1g/95mL (15°C) |
| Use | Intermediate of bezafibrate for organic synthesis |
| In vitro study | Tyramine is normally broken down in your body by an enzyme called MAO (monoamine oxidase). |
4-Hydroxyphenylethylamine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| RTECS | SJ5950000 |
| FLUKA BRAND F CODES | 10-23 |
| HS Code | 29214990 |
| Toxicity | LD50 intracervical in mouse: 30mg/kg |
4-Hydroxyphenylethylamine - Reference
| Reference Show more | 1. Leng Yixin, Wang Tongtong, Yin Zhibin, etc. Rapid determination of tyramine in rice wine by Laser Desorption/laser Post-ionization mass spectrometry [J]. Chinese Journal of Mass Spectrometry, 2018(1):46-52. 2. Quan Qinghua, Zhang Jiamei, Guo Xiaoyu, Sun Qianqian, Tian Changyu, Song Xingzhuo, Jiang kunxiu, Liu Yonggang, Gao Zengping. Fragmentation Mechanism of N-alkylamide derivatives by mass spectrometry [J]. Journal of Mass Spectrometry, 2020,41(05):402-410. 3. [IF = 5.753] Li Qingzhu et al."Transomic and metabologic Analyses reports That exogenic Methyl Jasmonate regulatory Galanthamine Biosynthesis in Lycoris." Front Plant Sci. 2021 Sep;0:1933 4. [IF = 7.514] Tian-tian Zhou et al."Novel carrier-mediated membrane-assisted three-phase liquid-liquid extraction coupled with liquid chromatography-mass spectrometry for the determination of eight biogenic amines in foods."Food Chem. 2022 Sep;387:132857 5. [IF=4.116] Yang Yan Hui et al."Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa."Planta. 2022 Mar;255(3):1-15 6. [IF=5.076] Jiahang Yu et al."A Colorimetric Ag Probe for Food Real-Time Visual Monitoring."Nanomaterials. 2022 Jan;12(9):1389 |
4-Hydroxyphenylethylamine - Introduction
Solubility: 1g/95ml water (15°C),1g/10ml boiling alcohol. Slightly soluble in benzene and xylene, soluble in ethanol.
Last Update：2022-10-16 17:25:42
4-Hydroxyphenylethylamine - Reference Information
| FEMA | 4215 | TYRAMINE |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| application | p-hydroxyphenethylamine is an amine organic substance, which can be used in the fields of medicine and organic synthesis. |
| Biological activity | Tyramine (4-hydroxyphenethylamine, para-tyramine, mydrial, uteramin) is a natural trace amine derived from amino acid tyrosine, which is a catecholamine release reagent. |
| Target | Value |
| hTAAR1 (COS-7 cells) | 34 nM(Ki) |
| Use | Used in organic synthesis; Bezafibrate intermediate (Intermediate of bezafibrate) Can enter the end of catecholaminergic (catecholaminergic) as a transmitter of camouflage. |
| production method | 1. this product is a tyrosine decarboxylation product, which exists in spoiled animal tissues, mature cheese and ergot. Tyrosine is decomposed or produced by spoilage bacteria. It can also be obtained by reducing p-hydroxyphenyl acetonitrile. 2. Tobacco: OR,27. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 15:16:50
Supplier List
Spot supply
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotationCAS: 51-67-2
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotationCAS: 51-67-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Tyramine Request for quotationCAS: 51-67-2
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Spot supply
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotationCAS: 51-67-2
Tel: 0086 15028179902
Email: sales@hbmojin.com
Mobile: 0086 15028179902
QQ: 2632046152
Wechat: 0086 15028179902
WhatsApp: 0086 15028179902
Multiple SpecificationsSpot supply
Product Name: Tyramine (Standard) Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotation
CAS: 51-67-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 51-67-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Multiple Specifications
Product Name: Tyramine Request for quotationCAS: 51-67-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Tyramine Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Tyramine Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Tyramine Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotationCAS: 51-67-2
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotationCAS: 51-67-2
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Spot supply
Product Name: Tyramine Request for quotationCAS: 51-67-2
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Spot supply
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotationCAS: 51-67-2
Tel: 0086 15028179902
Email: sales@hbmojin.com
Mobile: 0086 15028179902
QQ: 2632046152
Wechat: 0086 15028179902
WhatsApp: 0086 15028179902
Multiple SpecificationsSpot supply
Product Name: Tyramine (Standard) Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: 2-(4-Hydroxyphenyl)ethylamine Request for quotation
CAS: 51-67-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 51-67-2
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Multiple Specifications
Product Name: Tyramine Request for quotationCAS: 51-67-2
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: Tyramine Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Tyramine Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Tyramine Visit Supplier Webpage Request for quotationCAS: 51-67-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History