4-Hydroxytolbutamide-D9 - Names and Identifiers
4-Hydroxytolbutamide-D9 - Physico-chemical Properties
Molecular Formula | C12H9D9N2O4S
|
Molar Mass | 295.4 |
Melting Point | 100-103°C |
Solubility | Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | -20°C Freezer |
4-Hydroxytolbutamide-D9 - Introduction
Hydroxy Tolbutamide-d9 is a deuterated hydroxymethylglycinine in which the hydrogen atoms in its chemical structure are replaced by deuterium atoms. Its molecular formula is C12D9NO3S and its molecular weight is 233.34. It is a white crystalline solid.
The primary use of the Hydroxy Tolbutamide-d9 is as an internal standard in pharmacokinetic and pharmacokinetic studies. It is commonly used to label Tolbutamide, a non-insulinotropic releasing agent, for studies of drug metabolism and excretion.
The method for preparing Hydroxy Tolbutamide-d9 is mainly realized by the reaction of p-hydroxymethylglycopene with sodium deuteride. The generation of the deuterated species can be achieved by using a deuterated reagent, a deuterated oxidant, or a deuterium source in the preparation process.
Regarding the safety information of the Hydroxy Tolbutamide-d9, it is a chemical substance and should be handled and used in accordance with relevant laboratory safety procedures. Avoid skin contact, inhalation or ingestion during use. It should be stored in a dry, cool place to avoid contact with strong oxidants and strong acids. In case of accident or discomfort, seek medical help immediately.
Last Update:2024-04-09 21:54:55