4-IODO-7-AZA-1H-INDAZOLE
1H-Pyrazolo[3,4-b]pyridine, 4-iodo-
CAS: 861881-02-9
Molecular Formula: C6H4IN3
4-IODO-7-AZA-1H-INDAZOLE - Names and Identifiers
| Name | 1H-Pyrazolo[3,4-b]pyridine, 4-iodo- |
| Synonyms | 4-IODO-7-AZA-1H-INDAZOLE 4-IODO-1H-PYRAZOLO[3,4-B]PYRIDINE 1H-Pyrazolo[3,4-b]pyridine, 4-iodo- |
| CAS | 861881-02-9 |
| EINECS | 200-589-5 |
4-IODO-7-AZA-1H-INDAZOLE - Physico-chemical Properties
| Molecular Formula | C6H4IN3 |
| Molar Mass | 245.02 |
| Density | 2.219±0.06 g/cm3(Predicted) |
| Boling Point | 379.8±22.0 °C(Predicted) |
| pKa | 8.88±0.40(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
4-IODO-7-AZA-1H-INDAZOLE - Risk and Safety
| HS Code | 29332900 |
4-IODO-7-AZA-1H-INDAZOLE - Introduction
1H-Pyrazolo[3,4-b]pyridine, 4-iodo-is an organic compound with the chemical formula C8H5IN2. It is a heterocyclic compound having pyrazole and pyridine rings.
The following are the properties of 1H-Pyrazolo[3,4-b]pyridine, 4-iodo:
Appearance: White to light yellow crystal or powder
Melting point: about 170-173 ℃
Density: about 2.04g/cm³
Solubility: Soluble in common organic solvents such as chloroform and dichloromethane, insoluble in water
1H-Pyrazolo[3,4-b]pyridine, 4-iodo-has the following uses:
1. As an intermediate in organic synthesis, it can be used to synthesize other pyrazolo [3,4-b] pyridine compounds or related derivatives.
2. In the field of medicine, it may have anti-inflammatory, anti-tumor and antibacterial activities, so it can be used as a precursor of research drugs or the structural skeleton of drug molecules.
Preparation of 1H-Pyrazolo[3,4-b]pyridine, 4-iodo:
1H-Pyrazolo[3,4-b]pyridine, 4-iodo-can generally be synthesized by the following reaction-:
Under alkaline conditions, an appropriate amount of pyrazolo [3,4-b] pyridine compound is reacted with an iodinated reagent (such as methyl iodide or sodium iodide) to introduce an iodine atom at the 4-position of the pyrazolo [3,4-b] pyridine.
Safety information about 1H-Pyrazolo[3,4-b]pyridine, 4-iodo:
1. It is an organic compound that may be toxic to the human body. Contact with skin and inhalation of its dust should be avoided.
2. When using and handling, you should wear protective gloves and protective glasses, and ensure that you operate in a well-ventilated environment.
3. Waste should be disposed of in accordance with local regulations.
Please note that when using or handling any chemical substance, always follow correct operating procedures and safety measures, and learn more about the safety information of specific chemical substances.
The following are the properties of 1H-Pyrazolo[3,4-b]pyridine, 4-iodo:
Appearance: White to light yellow crystal or powder
Melting point: about 170-173 ℃
Density: about 2.04g/cm³
Solubility: Soluble in common organic solvents such as chloroform and dichloromethane, insoluble in water
1H-Pyrazolo[3,4-b]pyridine, 4-iodo-has the following uses:
1. As an intermediate in organic synthesis, it can be used to synthesize other pyrazolo [3,4-b] pyridine compounds or related derivatives.
2. In the field of medicine, it may have anti-inflammatory, anti-tumor and antibacterial activities, so it can be used as a precursor of research drugs or the structural skeleton of drug molecules.
Preparation of 1H-Pyrazolo[3,4-b]pyridine, 4-iodo:
1H-Pyrazolo[3,4-b]pyridine, 4-iodo-can generally be synthesized by the following reaction-:
Under alkaline conditions, an appropriate amount of pyrazolo [3,4-b] pyridine compound is reacted with an iodinated reagent (such as methyl iodide or sodium iodide) to introduce an iodine atom at the 4-position of the pyrazolo [3,4-b] pyridine.
Safety information about 1H-Pyrazolo[3,4-b]pyridine, 4-iodo:
1. It is an organic compound that may be toxic to the human body. Contact with skin and inhalation of its dust should be avoided.
2. When using and handling, you should wear protective gloves and protective glasses, and ensure that you operate in a well-ventilated environment.
3. Waste should be disposed of in accordance with local regulations.
Please note that when using or handling any chemical substance, always follow correct operating procedures and safety measures, and learn more about the safety information of specific chemical substances.
Last Update：2024-04-09 21:54:55
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CAS: 861881-02-9
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QQ: 3008007409
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CAS: 861881-02-9
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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