4-IODO-N-(2-THIENYLMETHYLENE)ANILINE - Names and Identifiers
4-IODO-N-(2-THIENYLMETHYLENE)ANILINE - Physico-chemical Properties
Molecular Formula | C11H8INS
|
Molar Mass | 313.16 |
Density | 1.65g/cm3 |
Boling Point | 384.8°C at 760 mmHg |
Flash Point | 186.5°C |
Vapor Presure | 8.8E-06mmHg at 25°C |
Refractive Index | 1.68 |
4-IODO-N-(2-THIENYLMETHYLENE)ANILINE - Introduction
(E)-4-Iodo-N-(thiophen-2-ylMethylene)aniline, also known as 4-Iodobenzyl 2-thienylcarbamate, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow crystal
-Molecular formula: C13H10INOS
-Molecular weight: 347.19g/mol
-Melting point: 112-114 ° C
-Boiling point: 427.8 ° C at 760 mmHg
-Density: 1.7g/cm³
-Solubility: Slightly soluble in water, soluble in organic solvents such as chloroform and dimethylformamide
Use:
(E)-4-Iodo-N-(thiophen-2-ylMethylene)aniline has some applications in the field of organic synthesis:
-As a catalyst: it can be used as a ligand for metal catalysts
-In drug synthesis: it can be used as an intermediate in organic synthesis, and has certain application potential in the preparation of drugs and biologically active compounds
Method:
The preparation of (E)-4-Iodo-N-(thiophen-2-ylMethylene)aniline usually involves the following steps:
1. First, 2-thiophenecarboxylic acid is reacted with an appropriate amount of base to obtain 2-thiophenecarboxylic acid.
2. Then, 2-thiophenol was reacted with 4-iodobenzoic anhydride under alkaline conditions to obtain (E)-4-Iodo-N-(thiophen-2-ylMethylene)aniline.
Safety Information:
(E)-4-Iodo-N-(thiophen-2-ylMethylene)aniline has limited safety information. As a chemical, it may be harmful to the environment and human body. During handling and use, follow relevant laboratory safety practices and wear appropriate personal protective equipment. In addition, pay close attention to its guidance and requirements for safe storage and disposal. In case of accident or discomfort, seek medical help immediately.
Last Update:2024-04-09 21:01:54