4-Iodo-2-fluoropyridine
2-fluoro-4-iodopyridine
CAS: 22282-70-8
Molecular Formula: C5H3FIN
4-Iodo-2-fluoropyridine - Names and Identifiers
| Name | 2-fluoro-4-iodopyridine |
| Synonyms | uoro-4-iodopyridine 2-Fluor-4-iodpyridin 2-Fluor-4-iodopyridine 4-Iodo-2-fluoropyridine 2-fluoro-4-iodopyridine 2-FLUORO-4-IODOPYRIDINE Pyridine, 2-fluoro-4-iodo- 2-Fluoro-4-iodopyridine AldrichCPR |
| CAS | 22282-70-8 |
| InChI | InChI=1/C5H3FIN/c6-5-3-4(7)1-2-8-5/h1-3H |
| InChIKey | ADPRIAVYIGHFSO-UHFFFAOYSA-N |
4-Iodo-2-fluoropyridine - Physico-chemical Properties
| Molecular Formula | C5H3FIN |
| Molar Mass | 222.99 |
| Density | 2.046±0.06 g/cm3(Predicted) |
| Melting Point | 57 °C |
| Boling Point | 223.0±20.0 °C(Predicted) |
| Flash Point | 88.6°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.147mmHg at 25°C |
| Appearance | Dark yellow crystal |
| Color | White to Light yellow |
| pKa | -1.81±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Light Sensitive |
| Refractive Index | 1.599 |
| MDL | MFCD03092926 |
| Physical and Chemical Properties | Dark yellow crystals |
4-Iodo-2-fluoropyridine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Harmful |
| Hazard Class | IRRITANT |
4-Iodo-2-fluoropyridine - Introduction
2-fluoro-4-iodopyridine is an organic compound with the chemical formula C5H3FIN. The following is a description of the nature, use, preparation and safety information of 2-fluoro-4-iodopyridine:
Nature:
-Appearance: A colorless to yellow crystal or solid.
-Melting point: about 95-97 degrees Celsius.
-Boiling point: About 220-222 degrees Celsius.
-Solubility: Can be dissolved in some organic solvents, such as alcohol and ether.
Use:
- 2-fluoro-4-iodopyridine can be used as an intermediate in organic synthesis, for the synthesis of drugs, pesticides and other organic compounds.
-It can also be used as a ligand in coordination chemistry and metal organic chemistry research.
Method:
The preparation of-2-fluoro-4-iodopyridine can be obtained by reacting 2-fluoro-4-chloropyridine with sodium iodide in an organic solvent.
-The reaction conditions can be carried out at high temperature.
Safety Information:
- 2-fluoro-4-iodopyridine is an organic compound and should be handled with caution.
-When handling or storing 2-fluoro-4-iodopyridine, you need to pay attention to the use of appropriate personal protective equipment, such as laboratory gloves and safety glasses.
-It should be kept away from fire and high temperature, and kept in a well-ventilated environment.
-When handling this compound, you should follow the correct laboratory operating procedures and strictly follow the relevant safety signs and guidelines.
-Swallowing or inhaling 2-fluoro-4-iodopyridine may be harmful to health, and direct contact with skin and eyes should be avoided.
Nature:
-Appearance: A colorless to yellow crystal or solid.
-Melting point: about 95-97 degrees Celsius.
-Boiling point: About 220-222 degrees Celsius.
-Solubility: Can be dissolved in some organic solvents, such as alcohol and ether.
Use:
- 2-fluoro-4-iodopyridine can be used as an intermediate in organic synthesis, for the synthesis of drugs, pesticides and other organic compounds.
-It can also be used as a ligand in coordination chemistry and metal organic chemistry research.
Method:
The preparation of-2-fluoro-4-iodopyridine can be obtained by reacting 2-fluoro-4-chloropyridine with sodium iodide in an organic solvent.
-The reaction conditions can be carried out at high temperature.
Safety Information:
- 2-fluoro-4-iodopyridine is an organic compound and should be handled with caution.
-When handling or storing 2-fluoro-4-iodopyridine, you need to pay attention to the use of appropriate personal protective equipment, such as laboratory gloves and safety glasses.
-It should be kept away from fire and high temperature, and kept in a well-ventilated environment.
-When handling this compound, you should follow the correct laboratory operating procedures and strictly follow the relevant safety signs and guidelines.
-Swallowing or inhaling 2-fluoro-4-iodopyridine may be harmful to health, and direct contact with skin and eyes should be avoided.
Last Update：2024-04-09 19:05:48
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