4-Isopropyl-L-phenylalanine
4-Isopropyl-L-phenylalanine
CAS: 216007-00-0
Molecular Formula: C12H17NO2
4-Isopropyl-L-phenylalanine - Names and Identifiers
4-Isopropyl-L-phenylalanine - Physico-chemical Properties
| Molecular Formula | C12H17NO2 |
| Molar Mass | 207.27 |
| Density | 1.105±0.06 g/cm3(Predicted) |
| Melting Point | 255 °C |
| Boling Point | 340.6±30.0 °C(Predicted) |
| pKa | 2.23±0.10(Predicted) |
4-Isopropyl-L-phenylalanine - Introduction
4-Isopropyl-L-phenylalanine is an organic compound with the chemical formula C11H15NO2. It has an isopropyl group and a phenylalanine group in its structure. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 4-Isopropyl-L-phenylalanine is a white crystalline powder.
-Melting point: about 165-170 ° C.
-Solubility: It is soluble in acids, alkalis and organic solvents.
Use:
-Pharmaceutical field: This compound is an unnatural amino acid, commonly used as an intermediate in drug synthesis. It can be used to synthesize peptide drugs, such as stimulant inhibitors, anti-tumor drugs, etc.
-Biochemistry: 4-isopropyl-phenylalanine can be used to study protein structure and function.
Method:
Generally, 4-Isopropyl-L-phenylalanine can be prepared by the following steps:
1. First, phenylalanine is reacted with isopropyl bromide under alkaline conditions to generate 4-isopropylphenylpropanol;
2. Then esterifying 4-isopropylphenylpropanol to generate 4-isopropylphenylpropionic acid;
3. Finally, 4-isopropylphenylpropionic acid is reacted with a reducing agent to obtain 4-Isopropyl-L-phenylalanine.
Safety Information:
-The toxicity and risk assessment of 4-Isopropyl-L-phenylalanine is unknown. But in general, for the operation of chemicals should pay attention to protect their own safety, the use of appropriate protective measures, such as wearing protective gloves, glasses and laboratory clothing.
-When using or handling this compound, it is recommended to follow Good Laboratory Practices and operate in a safe environment.
-If you accidentally take or come into contact with the compound, you should immediately seek medical advice and provide the doctor with the chemical label and safety data sheet of the compound.
Nature:
-Appearance: 4-Isopropyl-L-phenylalanine is a white crystalline powder.
-Melting point: about 165-170 ° C.
-Solubility: It is soluble in acids, alkalis and organic solvents.
Use:
-Pharmaceutical field: This compound is an unnatural amino acid, commonly used as an intermediate in drug synthesis. It can be used to synthesize peptide drugs, such as stimulant inhibitors, anti-tumor drugs, etc.
-Biochemistry: 4-isopropyl-phenylalanine can be used to study protein structure and function.
Method:
Generally, 4-Isopropyl-L-phenylalanine can be prepared by the following steps:
1. First, phenylalanine is reacted with isopropyl bromide under alkaline conditions to generate 4-isopropylphenylpropanol;
2. Then esterifying 4-isopropylphenylpropanol to generate 4-isopropylphenylpropionic acid;
3. Finally, 4-isopropylphenylpropionic acid is reacted with a reducing agent to obtain 4-Isopropyl-L-phenylalanine.
Safety Information:
-The toxicity and risk assessment of 4-Isopropyl-L-phenylalanine is unknown. But in general, for the operation of chemicals should pay attention to protect their own safety, the use of appropriate protective measures, such as wearing protective gloves, glasses and laboratory clothing.
-When using or handling this compound, it is recommended to follow Good Laboratory Practices and operate in a safe environment.
-If you accidentally take or come into contact with the compound, you should immediately seek medical advice and provide the doctor with the chemical label and safety data sheet of the compound.
Last Update：2024-04-09 21:01:54
