4-METHYLESCULETIN

Name	4-Methylesculetin
Synonyms	methylesculetin 4-METHYLESCULETIN 4-Methylesculetin 4-methylaesculetin METHYLESCULETIN, 4- 6,7-DIHYDROXY-4-METHYLCOUMARIN 6,7-Dihydroxy-4-methylcoumarin 6,7-DIHYDROXY-4-METHYL-CHROMEN-2-ONE 6,7-dihydroxy-4-methyl-2H-chromen-2-one (6,7-Dihydroxy-4-methylcoumarin)4-Methylesculetin 4-Methylesculetin, (6,7-Dihydroxy-4-methylcoumarin)
CAS	529-84-0
EINECS	208-470-0
InChI	InChI=1/C10H8O4/c1-5-2-10(13)14-9-4-8(12)7(11)3-6(5)9/h2-4,11-12H,1H3

Molecular Formula	C10H8O4
Molar Mass	192.17
Density	1.0825 (rough estimate)
Melting Point	274-276°C(lit.)
Boling Point	248.14°C (rough estimate)
Flash Point	190.7°C
Solubility	Soluble in hot water, alcohol, acetic acid, concentrated sulfuric acid and dilute alkali
Vapor Presure	6.46E-09mmHg at 25°C
Appearance	Yellow needle crystal
Color	Light brown
Maximum wavelength(λmax)	['348nm, 292nm']
BRN	162550
pKa	8.72(at 25℃)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.4440 (estimate)
MDL	MFCD00006859
Physical and Chemical Properties	Yellow needle-like crystals. The melting point was 272-274 °c. Soluble in hot water, alcohol, acetic acid, concentrated sulfuric acid and dilute alkali, the solution is blue fluorescence, in the case of ferric chloride is green.

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	2
RTECS	GN6384500
FLUKA BRAND F CODES	8
TSCA	Yes
HS Code	29322985
Hazard Class	IRRITANT

pH indicator color change ph range	Colorless (4.0) to blue 1 uorescent (6.2)
main applications	Electroluminescent device, photoresists, photography, analytical reagent, cosmetics, hair dye, shampoo, antioxidant, hypotensive agent, antiimfiammatroy agent, antiviral agent, multidrug resistance (MDR) modulator, inhibitory effect onmelanin biosynthesis, protective agent against DNA damage, antimutagenic agent, detection of tumor cell-specific cytotoxicity, antiproliferative againt against cancer cells, analysis of human pancreatice cancer cell activity, chondroprotective agent
EPA chemical information	Information provided by: ofmpub.epa.gov (external link)
biological activity	4-methylesculetin is a coumarin derivative with strong antioxidant and anti-inflammatory activities. 4-Methylesculetin inhibited myeloperoxidase (MPO) activity and decreased IL-6 levels.
Target	Value
use	as a fluorescent indicator.
Production method	Phenyltriacetate is formed from benzoquinone and acetic anhydride in the presence of concentrated acid. Under the action of dilute sulfuric acid, it reacts with ethyl acetoacetate, and the reactants are poured into ice water to precipitate the crude methyl heptine, and the filtered crystals are recrystallized with water to obtain the finished product.

Last Update：2024-04-09 21:04:16

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Product Name: 4-Methylesculetin Request for quotation
CAS: 529-84-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756

Multiple SpecificationsSpot supply

Product Name: 4-Methylesculetin Visit Supplier Webpage Request for quotation
CAS: 529-84-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

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4-METHYLESCULETIN

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