Name | 4-Nitroanisole |
Synonyms | 4-Nitroanisole 4-Methoxynitrobenzene (nitromethoxy)benzene 1-Methoxy-4-nitro-benzene |
CAS | 100-17-4 |
EINECS | 202-825-3 |
InChI | InChI=1/C7H7NO3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3 |
Molecular Formula | C7H7NO3 |
Molar Mass | 153.135 |
Density | 1.222g/cm3 |
Melting Point | 51-53℃ |
Boling Point | 260°C at 760 mmHg |
Flash Point | 134.6°C |
Water Solubility | 0.468 g/L (20℃) |
Vapor Presure | 0.0203mmHg at 25°C |
Refractive Index | 1.542 |
Use | Used as a dye and pharmaceutical intermediates, mainly used in the production of amino anisole, Blue Salt, VB, etc |
Hazard Symbols | Xn - Harmful |
Risk Codes | R68 - Possible risk of irreversible effects |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. |
UN IDs | UN 3458 |
Use:
Nitroanisole is widely used as a essence because it can give products a unique aroma. In addition, nitrobenzyl ether can also be used to synthesize certain dyes as a solvent and cleaning agent.
Preparation Method:
The preparation of nitroanisole can be obtained by the reaction of nitric acid and anisole. Usually, nitric acid is first mixed with concentrated sulfuric acid to become nitramine. Nitramine is then reacted with anisole under acidic conditions to give finally nitroanisole.
Safety Information:
Nitroanisole is an organic compound and should be used with caution. Its vapors and dust can irritate the eyes, skin and respiratory tract. Wear appropriate protective equipment such as gloves, goggles and protective masks during operation or contact to avoid skin and eye damage. In addition, nitroanisole has certain explosive properties and avoids contact with high heat, open flames and strong oxidants. During storage and use, a well-ventilated environment should be maintained and properly managed to prevent accidents. In case of accidental leakage, appropriate emergency measures shall be taken in time. Proper operating procedures and safety measures should be followed for the use and handling of any chemical.