4-Methyl-2-(piperazin-1-yl)pyridine

4-Methyl-2-(piperazin-1-yl)pyridine - Names and Identifiers

Name	1-(4-Methyl-2-pyridyl)piperazine
Synonyms	AKOS BBS-00003642 1-(4-Methyl-2-pyridyl)piperazine 1-[2-(4-METHYLPYRIDYL)]PIPERAZINE 1-(4-Methylpyridin-2-yl)piperazine 1-(4-methyl-2-pyridinyl)piperazine 4-Methyl-2-(piperazin-1-yl)pyridine 1-(4-METHYL-PYRIDIN-2-YL)-PIPERAZINE Piperazine, 1-(4-methyl-2-pyridinyl)- Piperazine, 1-(4-methyl-2-pyridinyl)- (9CI)
CAS	34803-67-3
InChI	InChI=1/C10H15N3/c1-9-2-3-12-10(8-9)13-6-4-11-5-7-13/h2-3,8,11H,4-7H2,1H3

4-Methyl-2-(piperazin-1-yl)pyridine - Physico-chemical Properties

Molecular Formula	C10H15N3
Molar Mass	177.25
Density	1.059±0.06 g/cm3(Predicted)
Boling Point	114-116°C 0,1mm
Flash Point	163.6°C
Vapor Presure	5.56E-05mmHg at 25°C
pKa	9.09±0.27(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.543
MDL	MFCD03412118

4-Methyl-2-(piperazin-1-yl)pyridine - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN3259
Hazard Note	Irritant
Hazard Class	8
Packing Group	III

4-Methyl-2-(piperazin-1-yl)pyridine - Introduction

1-(4-Methyl-2-pyridyl)piperazine is an organic compound with the chemical formula C12H17N3. It is a white solid, soluble in some organic solvents such as ethanol, methanol and dimethylformamide.

1-(4-Methyl-2-pyridyl)piperazine is often used as an intermediate in medicinal chemistry, and it can be used to synthesize various biologically active compounds. In the field of medicine, it is widely used in the research and production of antipsychotic, antidepressant and antianxiety drugs. In addition, it can also be used for synthetic dyes, spices and pesticides.

The preparation method of 1-(4-Methyl-2-pyridyl)piperazine is mainly obtained by reacting piperazine with 4-methyl -2-pyridine. First, piperazine is dissolved in an appropriate solvent, and then 4-methyl-2-pyridine is added to carry out the reaction. After completion of the reaction, the product was obtained by filtration and crystallization.

Regarding safety information, 1-(4-Methyl-2-pyridyl)piperazine should be properly handled in a laboratory or industrial production environment, following relevant safety procedures. It may cause irritation and discomfort when in contact with the eyes, skin and respiratory tract. Prolonged exposure to the substance should be avoided and suitable protective equipment, such as goggles and gloves, should be worn during use. If the compound is inhaled or ingested, seek medical help immediately.

Last Update：2024-04-09 21:01:54