4-Methyl-N1-(4-(pyridin-3-yl)pyriMidin-2-yl)benzene-1,3-diaMine - Names and Identifiers
4-Methyl-N1-(4-(pyridin-3-yl)pyriMidin-2-yl)benzene-1,3-diaMine - Physico-chemical Properties
Molecular Formula | C16H15N5
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Molar Mass | 277.32 |
4-Methyl-N1-(4-(pyridin-3-yl)pyriMidin-2-yl)benzene-1,3-diaMine - Introduction
1,3-benzenediamine, 4-methyl-N1-[4-(3-pyridinyl)-2-pyrimidinyl], also known as 1,3-phenylenediamine, 4-methyl-N1-[4-(3-pyridinyl)-2-pyrimidinyl], is an organic compound.
The properties of this compound are as follows:
-Appearance: White crystalline powder
-Molecular formula: C17H17N5
-Molecular weight: 295.36g/mol
-Melting point: about 123-125°C
-Solubility: Can be dissolved in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
the use of 1,3-phenylenediamine:
-Chemical reagent: As an intermediate in organic synthesis, it is widely used in the preparation of drugs and dyes.
-Anticancer drugs: 1,3-Phenylenediamine and its derivatives have anti-cancer effects and can be used for research and development of anti-tumor drugs.
-Biomarkers: 1,3-Phenylenediamine can bind to DNA and fluoresce, so it can be used for the preparation of biomarkers and fluorescent probes.
Preparation of 1,3-phenylenediamine:
1,3-Phenylenediamine can be obtained by reacting aniline with 2-amino -4-methylpyridine. First, aniline reacts with 2-amino-4-methylpyridine in the presence of hydrochloric acid to yield N-(3-amino-4-methylphenyl)-4-(pyridin-3-yl) pyridin -2-amine. Subsequently, this intermediate is subjected to a reduction reaction to form 1,3-phenylenediamine.
Safety Information:
- 1,3-Phenylenediamine may be irritating to the eyes and skin, and direct contact should be avoided.
-When using and handling, pay attention to personal protection, wear chemical protective gloves, goggles and protective clothing.
-Avoid inhaling dust or generating dust.
-Store away from ignition and oxidizing agents.
Last Update:2024-04-09 21:01:54