4-N-Boc-amino-piperidinecitrate

4-N-Boc-amino-piperidinecitrate - Names and Identifiers

Name	4-N-Boc-4-N-Methyl-aminopiperidine
Synonyms	BUTTPARK 906-17 4-Boc-methylaminopiperidine 4-Boc-4-methylaminopiperidine 4-N-Boc-amino-piperidinecitrate 4-N-BOC-4-N-METHYL-AMINOPIPERIDINE 4-N-Boc-4-N-Methyl-aminopiperidine tert-butyl Piperidin-4-ylmethylcarbamate tert-butyl methyl(piperidin-4-yl)carbamate 4-(Methylamino)piperidine, N4-BOC protected 4-AMINOPIPERIDINE-N-METHYL, N-BOC PROTECTED tert-Butyl N-methyl-N-(4-piperidyl)carbamate tert-butyl n-methyl-n-(4-piperidyl)carbamate 2-Methyl-2-propanyl methyl(4-piperidinyl)carbamate METHYL-PIPERIDIN-4-YL-CARBAMIC ACID TERT-BUTYL ESTER
CAS	108612-54-0
EINECS	672-392-7
InChI	InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13(4)9-5-7-12-8-6-9/h9,12H,5-8H2,1-4H3

4-N-Boc-amino-piperidinecitrate - Physico-chemical Properties

Molecular Formula	C11H22N2O2
Molar Mass	214.3
Density	1.01±0.1 g/cm3(Predicted)
Melting Point	50°C(lit.)
Boling Point	287.9±29.0 °C(Predicted)
Flash Point	127.9°C
Vapor Presure	0.00242mmHg at 25°C
Appearance	lens powder
pKa	10.05±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.485
MDL	MFCD02683051

4-N-Boc-amino-piperidinecitrate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36 - Wear suitable protective clothing. S44 -
HS Code	29339900
Hazard Note	Irritant

4-N-Boc-amino-piperidinecitrate - Reference Information

application

4-N-tert-butoxycarbonyl-4-N-methylaminopiperidine can be used as an intermediate in organic synthesis and pharmaceutical intermediates, mainly used in laboratory research and development process and chemical production process.

Preparation

Pd(OH)2(14.11mg,0.1mmol) is added to a solution of 1-(benzyloxycarbonyl)-4-(N-methyl-tert-butoxycarbonylamino) piperidine (0.35g,1mmol) in anhydrous MeOH(20mL), the resulting mixture was stirred at room temperature for 2 hours in an H2 atmosphere. After TLC shows that the starting material is consumed, the solvent is filtered through silica gel and the filtrate solvent is removed in vacuum to obtain crude 4-(N-methyl-tert-butoxycarbonylamino) piperidine (0.2g,60%).

Last Update：2024-04-09 21:01:54