4-Pyridylcarbinol
4-Pyridylcarbinol
CAS: 586-95-8
Molecular Formula: C6H7NO
4-Pyridylcarbinol - Names and Identifiers
4-Pyridylcarbinol - Physico-chemical Properties
| Molecular Formula | C6H7NO |
| Molar Mass | 109.13 |
| Density | 1.1143 (rough estimate) |
| Melting Point | 52-56 °C (lit.) |
| Boling Point | 107-110 °C/1 mmHg (lit.) |
| Flash Point | >230°F |
| Water Solubility | soluble |
| Vapor Presure | 0.00134mmHg at 25°C |
| Appearance | White to yellow crystals |
| Color | White to yellow |
| BRN | 107850 |
| pKa | 13.45±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Hygroscopic |
| Refractive Index | 1.5040 (estimate) |
| MDL | MFCD00006442 |
| Physical and Chemical Properties | Melting point 57 degrees C, boiling point 141(12mmHg). |
4-Pyridylcarbinol - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| RTECS | UT4691000 |
| FLUKA BRAND F CODES | 10-21 |
| TSCA | T |
| HS Code | 29333999 |
| Hazard Note | Irritant |
| Hazard Class | IRRITANT, HYGROSCOPI |
4-Pyridylcarbinol - Introduction
Soluble in water.
Last Update：2022-10-16 17:26:40
4-Pyridylcarbinol - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | 4-pyridyl methanol is also known as: pyridine-4-methanol, ω-hydroxy-4-piecoline, 4-(Hydroxymethyl)pyridine,4-Pyridinemethanol, 4-pyridyl carbinol, n-hydroxy-4-picoline, in recent years, 4-pyridylmethanol has been widely used as an intermediate of pesticide and medicine. 4-pyridyl methanol can be used for the preparation of 4-pyridinecarboxaldehyde. |
| Application | as an important pharmaceutical intermediate and fine chemical raw material, 4-pyridyl methanol has a wide range of applications and a broad market. In medicine, as an important pharmaceutical intermediate, 4-pyridine methanol can be used for the synthesis of exchange transfusion to Bisacodyl, is also the raw material for the synthesis of organic phosphate antidotes pralidoxime. In agriculture, 4-pyridinecarboxaldehyde is an essential intermediate for the synthesis of some acaricides; In the photosensitive industry, 4-pyridinecarboxaldehyde can be used for the synthesis of nitrogen-containing heterocyclic color photographic materials. |
| preparation | (a) the 4-methylpyridine reacts with glacial acetic acid and hydrogen peroxide at 70 ℃, the reaction time is 14h, and the molar ratio of 4-methylpyridine, glacial acetic acid and hydrogen peroxide is 1:3.5:3 to obtain 4-pyridinium nitrogen oxide; (B) the 4-pyridine nitrogen oxide reacts with acetic anhydride, the reaction temperature is 85 ℃, the reaction time is 6h, the molar ratio of the 4-pyridine nitrogen oxide to acetic anhydride is 1:2.5, 4-pyridine methyl acetate was obtained;(c) the reaction of 4-pyridine methyl acetate with potassium hydroxide solution, the reaction time is 4H, the molar ratio of the 2-pyridinecarboxylic acid methyl ester to potassium hydroxide was 1:1.5, and the reaction gave 4-pyridylmethanol. |
Last Update：2024-04-09 15:16:51
Supplier List
Spot supply
Product Name: 4-Pyridylcarbinol Request for quotationCAS: 586-95-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Donepezil Impurity 35 Visit Supplier Webpage Request for quotationCAS: 586-95-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 4-Pyridylcarbinol Request for quotation
CAS: 586-95-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 586-95-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: 4-Pyridinemethanol Visit Supplier Webpage Request for quotation
CAS: 586-95-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 586-95-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 4-Pyridylcarbinol Request for quotationCAS: 586-95-8
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Donepezil Impurity 35 Visit Supplier Webpage Request for quotationCAS: 586-95-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 4-Pyridylcarbinol Request for quotation
CAS: 586-95-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 586-95-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Product Name: 4-Pyridinemethanol Visit Supplier Webpage Request for quotation
CAS: 586-95-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 586-95-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History