Molecular Formula | C11H11ClN4O3S |
Molar Mass | 314.74804 |
Density | 1.548±0.06 g/cm3(Predicted) |
Melting Point | 200-202 °C(Solv: water (7732-18-5); ethanol (64-17-5)) |
Boling Point | 531.3±60.0 °C(Predicted) |
Appearance | Form Solid, color White to Light Gray |
pKa | -0.38±0.10(Predicted) |
Storage Condition | Refrigerator |
Use | Use is an intermediate of sulfamethoxine. |
Use methyl methoxyacetate and diethyl oxalate to condensed with the participation of sodium ethoxide to form methyl methoxybutanone diacid, and then heat to decarbonyl under reduced pressure to obtain methoxymalonic acid Methyl ester, the latter and formamide are condensed with sodium methoxide to obtain 5-methoxy-4, 6-dihydroxypyrimidine disodium, and then neutralized with hydrochloric acid to obtain 5-methoxy-4, 6-dihydroxypyrimidine, then use phosphorus trichloride to chlorinate hydroxyl, and condensation with sulfanilamide sodium salt to prepare the product.