4-Sulphamylacetophenone - Names and Identifiers
Name | 4-acetylbenzenesulfonamide
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Synonyms | BRN 2099150 4-Sulphamylacetophenone p-Acetobenzenesulfonamide p-acetobenzenesulfonamide p-acetyl-benzenesulfonamid 4-acetylbenzenesulfonamide 4-Acetylbenzenesulfonamide 4-acetyl-benzenesulfonamid P-ACETYLBENZENESULFONAMIDE p-Acetylbenzenesulfonamide 4-Acetylbenzenesulphonamide 4-ACETYLBENZENESULPHONAMIDE 4-ACETYL-BENZENESULFONAMIDE Benzenesulfonamide, 4-acetyl- Benzenesulfonamide, p-acetyl- (6CI,7CI,8CI) 4-11-00-00656 (Beilstein Handbook Reference)
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CAS | 1565-17-9
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EINECS | 216-363-5 |
InChI | InChI=1/C8H9NO3S/c1-6(10)7-2-4-8(5-3-7)13(9,11)12/h2-5H,1H3,(H2,9,11,12) |
4-Sulphamylacetophenone - Physico-chemical Properties
Molecular Formula | C8H9NO3S
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Molar Mass | 199.23 |
Density | 1.3589 (rough estimate) |
Melting Point | 177-179℃ |
Boling Point | 397.4±44.0 °C(Predicted) |
Flash Point | 194.2°C |
Water Solubility | soluble in water( 2650 mg/L). |
Vapor Presure | 1.59E-06mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Light yellow |
pKa | 9.70±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.5650 (estimate) |
4-Sulphamylacetophenone - Risk and Safety
Hazard Symbols | Xi - Irritant
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RTECS | DA9386000 |
Hazard Class | IRRITANT |
4-Sulphamylacetophenone - Introduction
4-acetylbenzenesulfonamide is an organic compound with the chemical formula C10H9NO3S. The following is a description of the nature, use, formulation and safety information of 4-acetylbenzenesulfonamide:
Nature:
-Appearance: 4-acetylbenzenesulfonamide is a white crystalline powder.
-Solubility: It is almost insoluble in water, but soluble in organic solvents such as ethanol, ether and dichloromethane.
-Melting point: The melting point of 4-acetylbenzenesulfonamide is about 166-168 ° C.
Use:
-Industrial use: 4-acetylbenzenesulfonamide is widely used as an intermediate for dyes, pigments and coatings.
-Medical use: It is also used to synthesize some drugs and bioactive molecules.
Method:
The preparation method of 4-acetylbenzenesulfonamide can be achieved by amidation reaction, the specific steps are as follows:
-Take benzenesulfonamide and acetic anhydride as raw materials.
-Under appropriate reaction conditions (such as heating, Catalyst, etc.), the amidation reaction of benzene sulfonamide and acetic anhydride occurs.
-After the reaction, the 4-acetylbenzenesulfonamide product is obtained through the steps of crystallization, filtration and drying.
Safety Information:
There are no clear toxicity data reported for the safety information of 4-acetylbenzenesulfonamide. However, when operating, you need to pay attention to the following:
-Avoid inhaling dust and contact with skin or eyes.
-During use, it is recommended to wear appropriate personal protective equipment, such as protective glasses, gloves and protective clothing.
-After use, waste should be disposed of properly and comply with local environmental regulations.
In general, use caution and follow the safety guidelines to ensure the safe use of 4-acetylbenzensulfonamide.
Last Update:2024-04-09 21:32:38