4-amino-2-hydroxybenzonitrile

4-amino-2-hydroxybenzonitrile - Names and Identifiers

Name	5-AMINO-2-HYDROXYBENZONITRILE
Synonyms	5-AMINO-2-HYDROXYBENZONITRILE 4-amino-2-hydroxybenzonitrile Benzonitrile, 4-amino-2-hydroxy-
CAS	67608-58-6

4-amino-2-hydroxybenzonitrile - Physico-chemical Properties

Molecular Formula	C7H6N2O
Molar Mass	134.14
Density	1.33±0.1 g/cm3(Predicted)
Melting Point	158-160 °C
Boling Point	362.0±32.0 °C(Predicted)
pKa	7.22±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

4-amino-2-hydroxybenzonitrile - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3439

4-amino-2-hydroxybenzonitrile - Introduction

It is an organic compound with the chemical formula C7H6N2O. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White to yellowish crystalline solid.
-Melting point: About 200-205 degrees Celsius.
-Solubility: Soluble in ethanol, dimethyl ether and chloroform, slightly soluble in water.

Use:
-is useful as a pharmaceutical intermediate and a starting material for the synthesis of organic compounds.
-It is often used as a derivative of P-Hydroxybenzoic acid in organic chemical synthesis, used in the synthesis of organic dyes, antiepileptic drugs, antidepressants, etc.

Method: The preparation method of
can be obtained by the reduction reaction of p-hydroxybenzonitrile. The specific steps are as follows:
1. The p-hydroxybenzonitrile and excess reducing agent (such as NaBH4) are reacted in an appropriate organic solvent.
2. After the reaction is completed, the reaction mixture is subjected to process treatment, such as cooling and filtering to obtain the product.
3. The product is further purified and crystallized to obtain pure calcium.

Safety Information:
There is limited safety information. It can be irritating and should be avoided from skin and eye contact. Appropriate safety measures should be taken during handling and storage, including wearing protective gloves and eye protection equipment. In use, should comply with the chemical safety procedures. If contact or inhalation occurs, seek medical attention immediately.

Last Update：2024-04-09 02:00:51