4-amino-4-(4-Methoxyphenyl)-Pyrimidine
2-Amino-4-(4-methoxyphenyl)pyrimidine
CAS: 99844-02-7
Molecular Formula: C11H11N3O
4-amino-4-(4-Methoxyphenyl)-Pyrimidine - Names and Identifiers
4-amino-4-(4-Methoxyphenyl)-Pyrimidine - Physico-chemical Properties
| Molecular Formula | C11H11N3O |
| Molar Mass | 201.22 |
| Density | 1.201g/cm3 |
| Boling Point | 434°C at 760 mmHg |
| Flash Point | 216.3°C |
| Vapor Presure | 9.8E-08mmHg at 25°C |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | IRRITANT |
| Refractive Index | 1.608 |
| MDL | MFCD00665912 |
4-amino-4-(4-Methoxyphenyl)-Pyrimidine - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
4-amino-4-(4-Methoxyphenyl)-Pyrimidine - Introduction
2-Amino-4-(4-methoxyphenyl)pyrimidine is a derivative of pyrimidine with the formula C12H12N4O. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-Amino-4-(4-methoxyphenyl)pyrimidine is a white crystalline solid.
-Solubility: Soluble in most organic solvents, such as methanol, ethanol and dichloromethane.
-Melting point: about 121-125 ℃.
Use:
2-Amino-4-(4-methoxyphenyl)pyrimidine can be used in the field of organic synthesis and medicine:
-In organic synthesis, it is often used as an intermediate to prepare other compounds.
-In the field of medicine, the compound has anti-tumor and antibacterial activities and can be used for research and development of drugs.
Preparation Method:
2-Amino-4-(4-methoxyphenyl)pyrimidine synthesis method is more complex, the following is a synthetic route:
-First, 2-amino-4-nitropyrimidine and p-methoxyphenylboronic acid undergo a series of reaction steps for substitution reaction.
-Finally, the target product is obtained by treatment such as reduction, crystallization, etc.
Safety Information:
- 2-Amino-4-(4-methoxyphenyl)pyrimidine has no obvious toxicity under normal operating conditions.
-However, when handling the compound and handling the compound, follow appropriate laboratory safety procedures and use personal protective equipment (such as gloves, safety glasses, and lab clothes).
-During storage and disposal, local codes and regulations should be followed to avoid undesirable reactions with other compounds or substances.
Nature:
-Appearance: 2-Amino-4-(4-methoxyphenyl)pyrimidine is a white crystalline solid.
-Solubility: Soluble in most organic solvents, such as methanol, ethanol and dichloromethane.
-Melting point: about 121-125 ℃.
Use:
2-Amino-4-(4-methoxyphenyl)pyrimidine can be used in the field of organic synthesis and medicine:
-In organic synthesis, it is often used as an intermediate to prepare other compounds.
-In the field of medicine, the compound has anti-tumor and antibacterial activities and can be used for research and development of drugs.
Preparation Method:
2-Amino-4-(4-methoxyphenyl)pyrimidine synthesis method is more complex, the following is a synthetic route:
-First, 2-amino-4-nitropyrimidine and p-methoxyphenylboronic acid undergo a series of reaction steps for substitution reaction.
-Finally, the target product is obtained by treatment such as reduction, crystallization, etc.
Safety Information:
- 2-Amino-4-(4-methoxyphenyl)pyrimidine has no obvious toxicity under normal operating conditions.
-However, when handling the compound and handling the compound, follow appropriate laboratory safety procedures and use personal protective equipment (such as gloves, safety glasses, and lab clothes).
-During storage and disposal, local codes and regulations should be followed to avoid undesirable reactions with other compounds or substances.
Last Update：2024-04-09 21:01:54
