4-bromo-3-nitrobenzoate

4-bromo-3-nitrobenzoate - Names and Identifiers

Name	3-nitro-4-bromobenzoic acid
Synonyms	RARECHEM AH CK 0042 4-bromo-3-nitrobenzoate 4-Bromo-3-nitrobenzoicaci 3-nitro-4-bromobenzoic acid 4-BROMO-3-NITROBENZOIC ACID 3-Nitro-4-bromobenzoic acid 4-Bromo-3-nitrobenzoic acid 2-Bromo-5-carboxynitrobenzene Benzoic acid, 4-bromo-3-nitro-
CAS	6319-40-0
InChI	InChI=1/C7H4BrNO4/c8-5-2-1-4(7(10)11)3-6(5)9(12)13/h1-3H,(H,10,11)/p-1

4-bromo-3-nitrobenzoate - Physico-chemical Properties

Molecular Formula	C7H4BrNO4
Molar Mass	246.01
Density	2.0176 (rough estimate)
Melting Point	202-204°C
Boling Point	340.9±32.0 °C(Predicted)
Flash Point	160°C
Vapor Presure	3.22E-05mmHg at 25°C
Appearance	White powder
Color	White to yellow
pKa	3.35±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.6200 (estimate)
MDL	MFCD00272137

4-bromo-3-nitrobenzoate - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
HS Code	29163990
Hazard Note	Irritant

4-bromo-3-nitrobenzoate - Introduction

3-nitro-4-bromobenzoic acid is an organic compound with the formula C7H4BrNO4.

Nature:
-Appearance: Colorless crystal or light yellow crystalline powder.
-melting point: 215-218 ℃.
-Solubility: Solubility in water is small, soluble in ethanol, ether and chloroform and other organic solvents.

Use:
3-nitro-4-bromobenzoic acid is an important organic synthesis intermediate, which is widely used in pharmaceutical synthesis and dye industry.
-Drug synthesis: can be used as a precursor for the synthesis of some non-steroidal anti-inflammatory drugs and other drugs.
-Dye industry: can be used for synthetic dyes and pigments.

Preparation Method:
3-nitro-4-bromobenzoic acid can be prepared by nitration of 4-bromobenzoic acid. The specific steps are as follows:
1. Dissolve 4-bromobenzoic acid in a mixed solution of nitric acid and glacial acetic acid.
2. Stir the reaction mixture at low temperature.
3. The product precipitated in the reaction mixture is filtered and washed, and then dried to obtain 3-nitro-4-bromobenzoic acid.

Safety Information:
3-nitro-4-bromobenzoic acid has a stimulating effect on the skin and eyes, and should be fully cleaned after contact. During use and storage, avoid inhaling its dust and wear protective equipment if necessary. In addition, 3-nitro-4-bromobenzoic acid may also cause harm to the environment, so care should be taken to comply with relevant environmental safety regulations.

Last Update：2024-04-09 20:52:54