4-bromo-Piperidine
4-bromo-Piperidine
CAS: 90633-18-4
Molecular Formula: C5H10BrN
4-bromo-Piperidine - Names and Identifiers
| Name | 4-bromo-Piperidine |
| Synonyms | 4-bromo-Piperidine 4-BROMO-PIPERIDINE Piperidine, 4-bromo- |
| CAS | 90633-18-4 |
4-bromo-Piperidine - Physico-chemical Properties
| Molecular Formula | C5H10BrN |
| Molar Mass | 164.04 |
| Density | 1.40 |
| Boling Point | 182℃ |
| Flash Point | 64℃ |
| pKa | 9.47±0.10(Predicted) |
4-bromo-Piperidine - Introduction
4-bromo-Piperidine is an organic compound with the chemical formula C5H10BrN, which is a bromo derivative of piperidine. The following is a description of the nature, use, preparation and safety information of 4-bromo-Piperidine:
Nature:
-Appearance: 4-bromo-Piperidine is a colorless liquid or crystalline solid.
-Melting point: about 30-31°C.
-Boiling point: about 191-195°C.
-Solubility: Can be dissolved in some organic solvents, such as ethanol and ether.
-Stability: 4-bromo-Piperidine is relatively stable to light, heat and air.
Use:
-Pharmaceutical field: 4-bromo-Piperidine can be used as an organic synthesis intermediate for the production of some drugs, such as antipsychotics and muscle relaxants.
-Research purposes: Due to the particularity of its chemical structure, 4-bromo-Piperidine is also commonly used in the study of organic synthesis reactions, such as hydrogenation, alkali metal catalysis and chiral synthesis.
Method:
The method of preparing 4-bromo-Piperidine usually includes the following steps:
1. react with hydrogen bromide or sodium bromate with piperidine to generate 4-bromo-Piperidine.
2. The progress of the reaction can be promoted by using an alkaline solution in the reaction.
3. Through the steps of extraction, distillation and purification, the pure 4-bromo-Piperidine product was obtained.
Safety Information:
- 4-bromo-Piperidine is an organic compound that may be harmful to health when in contact with skin, eyes or when inhaled. During operation or use, strictly follow safe operating procedures and use appropriate personal protective equipment.
-Prolonged or heavy exposure may have adverse effects on the central nervous system, respiratory system, or skin.
-During storage and handling, 4-bromo-Piperidine should be kept away from fire and oxidizing agents.
-Do not discharge this compound into water bodies or the environment and should be disposed of in accordance with local regulations.
Nature:
-Appearance: 4-bromo-Piperidine is a colorless liquid or crystalline solid.
-Melting point: about 30-31°C.
-Boiling point: about 191-195°C.
-Solubility: Can be dissolved in some organic solvents, such as ethanol and ether.
-Stability: 4-bromo-Piperidine is relatively stable to light, heat and air.
Use:
-Pharmaceutical field: 4-bromo-Piperidine can be used as an organic synthesis intermediate for the production of some drugs, such as antipsychotics and muscle relaxants.
-Research purposes: Due to the particularity of its chemical structure, 4-bromo-Piperidine is also commonly used in the study of organic synthesis reactions, such as hydrogenation, alkali metal catalysis and chiral synthesis.
Method:
The method of preparing 4-bromo-Piperidine usually includes the following steps:
1. react with hydrogen bromide or sodium bromate with piperidine to generate 4-bromo-Piperidine.
2. The progress of the reaction can be promoted by using an alkaline solution in the reaction.
3. Through the steps of extraction, distillation and purification, the pure 4-bromo-Piperidine product was obtained.
Safety Information:
- 4-bromo-Piperidine is an organic compound that may be harmful to health when in contact with skin, eyes or when inhaled. During operation or use, strictly follow safe operating procedures and use appropriate personal protective equipment.
-Prolonged or heavy exposure may have adverse effects on the central nervous system, respiratory system, or skin.
-During storage and handling, 4-bromo-Piperidine should be kept away from fire and oxidizing agents.
-Do not discharge this compound into water bodies or the environment and should be disposed of in accordance with local regulations.
Last Update：2024-04-09 21:04:16
