4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxaldehyde

Name	4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde
Synonyms	4-chloro-2-(Methylthio)pyriMidine-5-carbaldehyde 4-Chloro-2-(methylthio)-5-pyrimidinecarboxaldehyde 4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde 4-chloro-2-(Methylsulfanyl)pyriMidine-5-carbaldehyde 5-PyriMidinecarboxaldehyde, 4-chloro-2-(Methylthio)- 4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxaldehyde
CAS	148256-82-0

Molecular Formula	C6H5ClN2OS
Molar Mass	188.63
Density	1.44
Boling Point	315℃
Flash Point	144℃
pKa	-2.16±0.29(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C

Overview	4-chloro-2-methylthiopyrimidine-5-carboxylic acid is a carboxylic acid derivative useful as an organic intermediate. It has been reported that 4-chloro-2-methylthiopyrimidine-5-carboxylic acid can be used to prepare steroidal antiandrogen compounds, and pharmacological experiments have proved that such compounds have good anti-prostate cancer activity.
preparation	4-chloro-2-methylthiopyrimidine-5-carboxylic acid can be prepared by hydrolysis of ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate.

Last Update：2024-04-10 22:29:15