4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
4-Chloropyridine-3-boronic acid pinacol ester
CAS: 452972-15-5
Molecular Formula: C11H15BClNO2
4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Names and Identifiers
4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Physico-chemical Properties
| Molecular Formula | C11H15BClNO2 |
| Molar Mass | 239.51 |
| Density | 1.14±0.1 g/cm3(Predicted) |
| Melting Point | 110 |
| Boling Point | 326.8±27.0 °C(Predicted) |
| Flash Point | 151.4°C |
| Vapor Presure | 0.000402mmHg at 25°C |
| Appearance | solid |
| Color | white to off-white |
| pKa | 3.19±0.10(Predicted) |
| Storage Condition | Keep Cold |
| Refractive Index | 1.505 |
| MDL | MFCD06798247 |
4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. |
| TSCA | No |
| Hazard Note | Irritant/Keep Cold |
| Hazard Class | IRRITANT |
4-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Introduction
4-Chloropyridine-3-boronic acid pinacol ester is an organic compound with the chemical formula C11H14BClNO2. Its nature is as follows:
Appearance: Colorless crystalline solid
Solubility: Soluble in organic solvents, such as methanol, ethanol, dimethyl sulfoxide, etc.
Density: approx. 1.22g/cm³
Melting point: about 82-86°C
Molecular weight: 245.51
4-Chloropyridine-3-boronic acid pinacol ester has the following uses:
1. As an important reagent in organic synthesis, it can be used to construct the chemical reaction of aromatic ring.
2. can be used to synthesize a variety of organic compounds containing pyridine structure, such as pharmaceutical intermediates and pesticide active ingredients.
3. for the synthesis and analysis of compounds in pharmaceutical research and chemical biology research.
4. can be used as a catalyst to participate in the coupling reaction catalyzed by copper.
the method for preparing 4-Chloropyridine-3-boronic acid pinacol ester generally uses boric acid, pinacol and 4-chloropyridine as raw materials and is generated by heating reaction. The specific preparation process can refer to the relevant literature of organic chemistry.
Regarding safety information, 4-Chloropyridine-3-boronic acid pinacol ester is relatively stable under general conditions, but the following safety matters still need to be paid attention:
1. in the operation should pay attention to personal protective measures, such as wearing protective glasses, masks and gloves.
2. avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
3. avoid inhalation of dust or gas, should be in a well ventilated place to operate.
4. storage should be sealed, away from fire and high temperature environment.
5. the use of the process should strictly abide by the safety procedures, to avoid mixing with other chemicals.
These safety information are for reference only. Please refer to the relevant chemical substance safety manual and operation guide for specific use.
Appearance: Colorless crystalline solid
Solubility: Soluble in organic solvents, such as methanol, ethanol, dimethyl sulfoxide, etc.
Density: approx. 1.22g/cm³
Melting point: about 82-86°C
Molecular weight: 245.51
4-Chloropyridine-3-boronic acid pinacol ester has the following uses:
1. As an important reagent in organic synthesis, it can be used to construct the chemical reaction of aromatic ring.
2. can be used to synthesize a variety of organic compounds containing pyridine structure, such as pharmaceutical intermediates and pesticide active ingredients.
3. for the synthesis and analysis of compounds in pharmaceutical research and chemical biology research.
4. can be used as a catalyst to participate in the coupling reaction catalyzed by copper.
the method for preparing 4-Chloropyridine-3-boronic acid pinacol ester generally uses boric acid, pinacol and 4-chloropyridine as raw materials and is generated by heating reaction. The specific preparation process can refer to the relevant literature of organic chemistry.
Regarding safety information, 4-Chloropyridine-3-boronic acid pinacol ester is relatively stable under general conditions, but the following safety matters still need to be paid attention:
1. in the operation should pay attention to personal protective measures, such as wearing protective glasses, masks and gloves.
2. avoid contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
3. avoid inhalation of dust or gas, should be in a well ventilated place to operate.
4. storage should be sealed, away from fire and high temperature environment.
5. the use of the process should strictly abide by the safety procedures, to avoid mixing with other chemicals.
These safety information are for reference only. Please refer to the relevant chemical substance safety manual and operation guide for specific use.
Last Update：2024-04-09 20:02:46
Supplier List
Product Name: 4-Chloropyridine-3-Boronic Acid Pinacol Ester Visit Supplier Webpage Request for quotation
CAS: 452972-15-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 452972-15-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 4-Chloropyridine-3-Boronic Acid Pinacol Ester Visit Supplier Webpage Request for quotation
CAS: 452972-15-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 452972-15-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History