4-chloro-8-(trifluoromethyl)quinoline

4-chloro-8-(trifluoromethyl)quinoline - Names and Identifiers

Name	4-chloro-8-(trifluoromethyl)quinoline
Synonyms	5,5,5-trifluoronorvaline 4-Chloro-8-(trifluoromethyl)quinoline 4-chloro-8-(trifluoromethyl)quinoline 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE 4-Chloro-8-(trifluoroMethyl)quinolline Quinoline, 4-chloro-8-(trifluoromethyl)-
CAS	23779-97-7
EINECS	245-880-9
InChI	InChI=1/C5H8F3NO2/c6-5(7,8)2-1-3(9)4(10)11/h3H,1-2,9H2,(H,10,11)

4-chloro-8-(trifluoromethyl)quinoline - Physico-chemical Properties

Molecular Formula	C10H5ClF3N
Molar Mass	231.6
Density	1.356g/cm³
Melting Point	80-82°C(lit.)
Boling Point	206.7°C at 760 mmHg
Flash Point	78.8°C
Water Solubility	Low solubility in water.
Solubility	Chloroform, Methanol
Vapor Presure	0.0947mmHg at 25°C
Appearance	Solid
Color	Brown
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.402
MDL	MFCD00134578

4-chloro-8-(trifluoromethyl)quinoline - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29334900
Hazard Class	IRRITANT

4-chloro-8-(trifluoromethyl)quinoline - Introduction

4-chloro-8-(trifluoromethyl)quinoline is a compound with a specific structure. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: 4-chloro-8-(trifluoromethyl)quinoline is a colorless to light yellow crystalline solid.
-Melting point: Its melting point is usually between 50-54 degrees Celsius.
-Solubility: This compound has good solubility and is soluble in many organic solvents, such as methanol, ethanol and dichloromethane.

Use:
- 4-chloro-8-(trifluoromethyl)quinoline has a wide range of applications in the field of organic synthesis. It can be used as a synthetic intermediate for dyes and pigments.
-The compound also has potential application value in the field of medicine. Studies have shown that it may have therapeutic potential for certain diseases, such as inhibiting the growth of certain tumors.

Method:
- 4-chloro-8-(trifluoromethyl)quinoline is generally prepared by organic chemical synthesis methods. One commonly used method is by reacting 2-bromo-4-chloroquinoline with methyl trifluorocarbamate.

Safety Information:
There are no clear data and evaluation of the toxicity and danger of -4-chloro-8-(trifluoromethyl)quinoline. When performing laboratory operations, appropriate personal protective measures should be taken, such as wearing appropriate gloves and eye protection equipment.
-It should be stored in a dry, clean, airtight container, away from heat and fire sources, and with oxidizing agents, strong acid and alkali substances such as isolation storage.
-When using this compound, strictly follow the relevant safety procedures and properly dispose of waste.

Last Update：2024-04-09 02:00:44