4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide
clopamide
CAS: 636-54-4
Molecular Formula: C14H20ClN3O3S
4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide - Names and Identifiers
| Name | clopamide |
| Synonyms | Aquex Adurix DT-327 CLOPAMIDE clopamide Brinaldix 4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide 4-CHLORO-N-[2,6-DIMETHYLPIPERIDINYL]-3-SULFAMOYLBENZAMIDE 4-chloro-N-(2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide 4-Chloro-N-[(2R,6S)-2,6-dimethylpiperidino)-3-sulfamoylbenzamide 4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide |
| CAS | 636-54-4 |
| EINECS | 211-261-7 |
| InChI | InChI=1/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+ |
4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide - Physico-chemical Properties
| Molecular Formula | C14H20ClN3O3S |
| Molar Mass | 345.84 |
| Density | 1.39±0.1 g/cm3(Predicted) |
| Melting Point | 248-249℃ |
| Solubility | Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly) |
| Appearance | neat |
| Color | Pale Yellow to Light Yellow |
| pKa | 9.41±0.60(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.613 |
| Use | Urinary system drugs/diuretics and dehydratants/diuretics/intermediate diuretics |
| In vitro study | Clopamide is actively secreted by renal tubular cells and the True Tubular Excretion Fraction (TTEF) value is 10%. |
| In vivo study | The venoconstrictor response to bradykinin is attenuated after oral administration of Clopamide (0.5 mg/kg), and by concomitant local infusion of cyclosporine-A (1-10 μg/min) in conscious dogs. |
4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 42/43 - May cause sensitization by inhalation and skin contact. |
| Safety Description | 36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | CV2338875 |
Supplier List
Multiple Specifications
Product Name: Clopamide Visit Supplier Webpage Request for quotationCAS: 636-54-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: Clopamide Visit Supplier Webpage Request for quotationCAS: 636-54-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History