4-chloroacetoacetanilide
4-chloroacetoacetanilide
CAS: 39082-00-3
Molecular Formula: C10H10ClNO2
4-chloroacetoacetanilide - Names and Identifiers
| Name | 4-chloroacetoacetanilide |
| Synonyms | 4-chloroacetoacetanilide α-(Chloroacetyl)acetanilide N-Phenyl-4-chloro-3-oxobutyramide Butanamide, 4-chloro-3-oxo-N-phenyl- |
| CAS | 39082-00-3 |
| EINECS | 254-276-4 |
4-chloroacetoacetanilide - Physico-chemical Properties
| Molecular Formula | C10H10ClNO2 |
| Molar Mass | 211.64 |
| Density | 1.2414 (rough estimate) |
| Boling Point | 303°C (rough estimate) |
| Refractive Index | 1.5500 (estimate) |
4-chloroacetoacetanilide - Introduction
4-chloroacetoacetanilide (4-chloroacetoacetanilide) is an organic compound with the molecular formula C10H10ClNO2.
Its nature:
-Appearance: White crystalline solid
-Melting point: 148-150 ° C
-water-soluble: slightly soluble in water, soluble in organic solvents such as alcohol, ether and ketone.
-chemical properties: 4-chloroacetanilide can be used as a coupling agent of dibasic acid anhydride, and react with amines to form pigments and dyes.
Its purpose:
-Pharmaceutical field: 4-chloroacetoacetanilide can be used as an intermediate for dyes, and can also be used to synthesize intermediates and ligands for organic synthesis.
-Research Laboratory: It is used as a substrate and reagent for organic synthesis reactions.
Preparation Method:
The preparation of 4-chloroacetoacetanilide is generally carried out by the following steps:
1. Obtaining aniline (C6H7NH2) and 4-chloroacetic acid (C2H3ClO2).
2. Under appropriate temperature and conditions, aniline is reacted with 4-chloroacetic acid to generate 4-chloroacetoacetanilide.
Safety Information:
-4-Chloroacetanilide is a chemical and should be stored in a dry, well-ventilated place. Avoid contact with fire and oxidant.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use.
-In case of inhalation, skin contact or ingestion, seek medical advice immediately and bring the product container or label.
-Please dispose the waste of this chemical in accordance with local regulations to avoid harm to the environment and human body.
Its nature:
-Appearance: White crystalline solid
-Melting point: 148-150 ° C
-water-soluble: slightly soluble in water, soluble in organic solvents such as alcohol, ether and ketone.
-chemical properties: 4-chloroacetanilide can be used as a coupling agent of dibasic acid anhydride, and react with amines to form pigments and dyes.
Its purpose:
-Pharmaceutical field: 4-chloroacetoacetanilide can be used as an intermediate for dyes, and can also be used to synthesize intermediates and ligands for organic synthesis.
-Research Laboratory: It is used as a substrate and reagent for organic synthesis reactions.
Preparation Method:
The preparation of 4-chloroacetoacetanilide is generally carried out by the following steps:
1. Obtaining aniline (C6H7NH2) and 4-chloroacetic acid (C2H3ClO2).
2. Under appropriate temperature and conditions, aniline is reacted with 4-chloroacetic acid to generate 4-chloroacetoacetanilide.
Safety Information:
-4-Chloroacetanilide is a chemical and should be stored in a dry, well-ventilated place. Avoid contact with fire and oxidant.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use.
-In case of inhalation, skin contact or ingestion, seek medical advice immediately and bring the product container or label.
-Please dispose the waste of this chemical in accordance with local regulations to avoid harm to the environment and human body.
Last Update：2024-04-09 01:59:53
