4-dichloro-8-fluoroquinazoline

4-dichloro-8-fluoroquinazoline - Names and Identifiers

Name	2,4-dichloro-8-fluoroquinazoline
Synonyms	4-dichloro-8-fluoroquinazoline 2,4-Dichloro-8-fluoroquinazoline 2,4-dichloro-8-fluoroquinazoline 2,4-DICHLORO-8-FLUORO-QUINAZOLINE Quinazoline, 2,4-dichloro-8-fluoro- 2,4- two-8- chlorinefluorinequinazoline
CAS	959237-64-0
InChI	InChI=1/C8H3Cl2FN2/c9-7-4-2-1-3-5(11)6(4)12-8(10)13-7/h1-3H

4-dichloro-8-fluoroquinazoline - Physico-chemical Properties

Molecular Formula	C8H3Cl2FN2
Molar Mass	217.03
Density	1.571g/cm³
Boling Point	277.3°C at 760 mmHg
Flash Point	121.5°C
Vapor Presure	0.00772mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.644

4-dichloro-8-fluoroquinazoline - Introduction

2, is an organic compound, its chemical formula is C9H4Cl2FN. The following is a description of its nature, use, preparation and safety information:

Nature:
2, is a solid with white to light yellow crystals. It is stable at room temperature and insoluble in water, but soluble in organic solvents such as ethanol and methylene chloride. It has the smell of smoke, inhalation and contact irritation.

Use:
2, is widely used in the field of drugs and pesticides. It can be used as an intermediate for the synthesis of other drug molecules, such as anti-tumor drugs, antibacterial drugs and antiviral drugs. In addition, it can also be used as a raw material and intermediate for pesticides to control pests and weeds on crops.

Preparation Method:
The preparation method of 2, is relatively complicated. A common synthesis method is to start with 3-chloro-4-bromonaphthalene, and synthesize it through multiple steps such as cyanation reaction, reduction and fluorination reaction. This process requires attention to safe operation and instrumentation, as some intermediates and reactants may be toxic.

Safety Information:
2, is an organic compound with certain toxicity. Contact or inhalation of its dust or solution may cause irritation, harmful to the skin, eyes and respiratory system. Wear appropriate protective measures such as gloves, safety glasses and respiratory protection when handling the compound. At the same time, when storing and handling this compound, relevant safe handling guidelines and regulations should be followed. If necessary, professionals or laboratory managers should be consulted for more detailed safety information and operational recommendations.

Last Update：2024-04-09 21:11:58