4-hydroxy-2-Piperidinone
4-Hydroxypiperidin-2-one
CAS: 476014-76-3
Molecular Formula: C5H9NO2
4-hydroxy-2-Piperidinone - Names and Identifiers
| Name | 4-Hydroxypiperidin-2-one |
| Synonyms | 4-hydroxy-2-Piperidi 4-Hydroxy-2-piperidone 4-Hydroxypiperidin-2-on 4-hydroxy-2-Piperidinone 4-Hydroxypiperidin-2-one 4-Hydroxy-2-Piperidinone 4-Hydroxy-piperidin-2-one 2-Piperidinone, 4-hydroxy- 2-piperidinone, 4-hydroxy- |
| CAS | 476014-76-3 |
| InChI | InChI=1/C5H9NO2/c7-4-1-2-6-5(8)3-4/h4,7H,1-3H2,(H,6,8) |
4-hydroxy-2-Piperidinone - Physico-chemical Properties
| Molecular Formula | C5H9NO2 |
| Molar Mass | 115.13 |
| Density | 1.199±0.06 g/cm3(Predicted) |
| Melting Point | 165-168°C |
| Boling Point | 352.3±35.0 °C(Predicted) |
| Flash Point | 166.8°C |
| Solubility | Methanol (Slightly, Sonicated) |
| Vapor Presure | 2.28E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 14.01±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.497 |
4-hydroxy-2-Piperidinone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
4-hydroxy-2-Piperidinone - Introduction
4-Hydroxypiperidin-2-one(4-Hydroxypiperidin-2-one) is an organic compound with the chemical formula C5H9NO2. It is a white crystalline solid with a distinctive amine and bitter taste. The following is a detailed description of the nature, use, preparation and safety information of 4-Hydroxypiperidin-2-one:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 115.13g/mol
-Melting Point: 128-130°C
-Boiling point: 383.3°C
-Density: 1.246g/cm³
-Solubility: Soluble in water and some organic solvents
Use:
4-Hydroxypiperidin-2-one is mainly used in organic synthesis reactions as an important intermediate. It is often used in the synthesis of other compounds, such as drugs, dyes and pesticides. Because of its unique molecular structure, it has a wide range of applications in many organic synthesis reactions.
Preparation Method:
The preparation method of 4-Hydroxypiperidin-2-one is relatively simple. The following is a commonly used synthesis method:
2-Piperidinone is reacted with excess sodium hydroxide in an appropriate solvent to produce 4-Hydroxypiperidin-2-one. The reaction is usually carried out under heating, and the pure product is obtained after work-up.
Safety Information:
For safety information on 4-Hydroxypiperidin-2-one, the following recommendations need to be followed:
-Contact: Avoid skin contact. If you come into contact with the skin, you should wash it with plenty of water immediately.
-Inhalation: Avoid inhaling the dust or vapor of the compound, and the working environment should have good ventilation conditions.
-Food safety: Avoid ingesting or swallowing the substance, and consult further about safety if necessary.
Nature:
-Appearance: White crystalline solid
-Molecular weight: 115.13g/mol
-Melting Point: 128-130°C
-Boiling point: 383.3°C
-Density: 1.246g/cm³
-Solubility: Soluble in water and some organic solvents
Use:
4-Hydroxypiperidin-2-one is mainly used in organic synthesis reactions as an important intermediate. It is often used in the synthesis of other compounds, such as drugs, dyes and pesticides. Because of its unique molecular structure, it has a wide range of applications in many organic synthesis reactions.
Preparation Method:
The preparation method of 4-Hydroxypiperidin-2-one is relatively simple. The following is a commonly used synthesis method:
2-Piperidinone is reacted with excess sodium hydroxide in an appropriate solvent to produce 4-Hydroxypiperidin-2-one. The reaction is usually carried out under heating, and the pure product is obtained after work-up.
Safety Information:
For safety information on 4-Hydroxypiperidin-2-one, the following recommendations need to be followed:
-Contact: Avoid skin contact. If you come into contact with the skin, you should wash it with plenty of water immediately.
-Inhalation: Avoid inhaling the dust or vapor of the compound, and the working environment should have good ventilation conditions.
-Food safety: Avoid ingesting or swallowing the substance, and consult further about safety if necessary.
Last Update：2024-04-09 21:04:16
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