4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-n
Flocoumafen
CAS: 90035-08-8
Molecular Formula: C33H25F3O4
4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-n - Names and Identifiers
4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-n - Physico-chemical Properties
| Molecular Formula | C33H25F3O4 |
| Molar Mass | 542.54 |
| Density | 1.2 g/cm3 |
| Melting Point | 181 °C |
| Boling Point | 672.4±55.0 °C(Predicted) |
| Flash Point | 23°C |
| Water Solubility | 1.1 mg l-1 |
| Vapor Presure | 1.33 x l0-10 Pa (25 °C) |
| Appearance | neat |
| pKa | 4.50±1.00(Predicted) |
| Physical and Chemical Properties | The appearance is white powder, m.p.161 ~ 162 ℃, relative density 1.23, flash point 200 ℃, vapor pressure 2.66 × 10-6Pa(1.33 × 10-11Pa) (25 ℃). Soluble in organic solvents such as acetone, ethanol, chloroform, xylene, etc., with a solubility of more than 10g/L; Solubility in water 1.1mg/L. Stable storage under normal conditions. |
4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-n - Risk and Safety
| Risk Codes | R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. R48/23/24/25 - R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | 3027 |
| WGK Germany | 3 |
| RTECS | DJ3100300 |
| Hazard Class | 6.1(a) |
| Packing Group | I |
| Toxicity | LD50 in rats, mice, rabbits (mg/kg): 0.25, 0.8, 0.2 orally (Bowler) |
4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-n - References
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| toxicity | the original drug has no irritating effect on skin and eyes for acute oral LD50 of 0.25~0.4 mg/kg and acute percutaneous LD500.54 mg/kg in rats. Rainbow trout LC500.0091 mg/L, mallard oral LD501.7 mg/kg. |
| use | second generation anticoagulant. It has the advantages of strong toxicity, good palatability and significant deratization effect. It can prevent domestic rats, wild rats and other types of rodenticide resistant rat species. When using, 0.1% powder can be prepared into 0.005% poison bait. After 19 portions of grain bait are soaked and slightly cooled, 0.1% fluororadione powder is added and fully mixed for use. Prevention and control of domestic mice 1~3 bait points per room, 3~5g per point, if necessary 3~6 days later supplement; For the prevention and control of wild rats, a point is set at 50m2, and 5~10g of poison bait is pushed and released at every point. Fluorine ketone is highly toxic, pay attention to safety when using it. |
| Production method | The preparation of 4-hydroxycoumarin is shown in the preparation method of scutamine. 3-[4-(4-trifluoromethylbenzyloxy) phenyl]-1,2,3, 4-tetrahydro-1-naphthol was prepared by reacting 4-trifluoromethylbromide with naphtholone in DMF at room temperature, and the reaction product was reduced with NaBH4. Synthesis of fluororicone 3-[4-(4-trifluoromethylbenzyloxy) phenyl]-1,2,3, 4-tetrahydro-1-naphthol and 4-hydroxycoumarin In the presence of p-methyl benzene sulfonic acid condensation, fluororicone was prepared. |
| category | pesticide |
| toxicity classification | highly toxic |
| acute toxicity | oral-rat LD50: 0.25 mg/kg; Oral-mouse LD50: 0.80 mg/kg |
| flammability hazard characteristics | open flame combustible; heated decomposition of toxic fluoride gas |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from food raw materials storage and transportation |
| fire extinguishing agent | sand, dry powder, foam |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 22:01:39
