4-hydroxy-7-methoxyquinoline-6-carboxamide
7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxaMide
CAS: 417724-81-3
Molecular Formula: C11H10N2O3
4-hydroxy-7-methoxyquinoline-6-carboxamide - Names and Identifiers
4-hydroxy-7-methoxyquinoline-6-carboxamide - Physico-chemical Properties
| Molecular Formula | C11H10N2O3 |
| Molar Mass | 218.21 |
| Density | 1.324±0.06 g/cm3(Predicted) |
| Boling Point | 372.1±42.0 °C(Predicted) |
| pKa | 15.36±0.20(Predicted) |
| Use | Uses 1, 4-dihydro-7-methoxy-4-oxo-6-quinolinformamide is a metabolite of lenvatinib, an oral multi-receptor tyrosine kinase inhibitor, including VEGF, FGF and SCF receptors. |
4-hydroxy-7-methoxyquinoline-6-carboxamide - Upstream Downstream Industry
4-hydroxy-7-methoxyquinoline-6-carboxamide - Introduction
7-methoxy-4-ox-1 (7-Methoxy-4-oxo-1) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow solid.
-Solubility: Soluble in most organic solvents, such as ethanol, chloroform and dichloromethane.
-Melting point: About 171-174 ° C.
Use:
-Chemical reagents: commonly used as intermediates in organic synthesis.
-Drug research: The compound has certain biological activity and can be used in the fields of drug development and efficacy evaluation.
Method:
1. From aniline:
-Aniline is reacted with acetic acid, acetic anhydride and hydrochloric acid to form acetanilide.
-Acetanilide reacts with 1,4-benzoquinone to produce 1,4-dihydro-7-acetylquinoline.
-Finally, 1,4-dihydro-7-acetylquinoline is oxidized and methylated to obtain 7-Methoxy-4-oxo-1.
Safety Information:
-The compound may cause certain harm to the human body, such as irritation to the eyes, skin and inhalation routes.
-During use, avoid direct contact with skin and eyes, and follow relevant safety procedures.
-During storage, the compound should be stored in a sealed container, away from heat and fire sources.
Please note that it is recommended to consult reliable chemical information for specific properties, uses, manufacturing methods and safety information of chemicals.
Nature:
-Appearance: Colorless or light yellow solid.
-Solubility: Soluble in most organic solvents, such as ethanol, chloroform and dichloromethane.
-Melting point: About 171-174 ° C.
Use:
-Chemical reagents: commonly used as intermediates in organic synthesis.
-Drug research: The compound has certain biological activity and can be used in the fields of drug development and efficacy evaluation.
Method:
1. From aniline:
-Aniline is reacted with acetic acid, acetic anhydride and hydrochloric acid to form acetanilide.
-Acetanilide reacts with 1,4-benzoquinone to produce 1,4-dihydro-7-acetylquinoline.
-Finally, 1,4-dihydro-7-acetylquinoline is oxidized and methylated to obtain 7-Methoxy-4-oxo-1.
Safety Information:
-The compound may cause certain harm to the human body, such as irritation to the eyes, skin and inhalation routes.
-During use, avoid direct contact with skin and eyes, and follow relevant safety procedures.
-During storage, the compound should be stored in a sealed container, away from heat and fire sources.
Please note that it is recommended to consult reliable chemical information for specific properties, uses, manufacturing methods and safety information of chemicals.
Last Update：2024-04-09 15:18:03
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Spot supply
Product Name: Lenvatinib Impurity 19 Visit Supplier Webpage Request for quotationCAS: 417724-81-3;2110414-05-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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Raw Materials for 4-hydroxy-7-methoxyquinoline-6-carboxamide