4-iodo-2-(trifluoromethyl)pyridine

4-iodo-2-(trifluoromethyl)pyridine - Names and Identifiers

Name	4-iodo-2-(trifluoromethyl)pyridine
Synonyms	4-IODE-2-(TRIFLUOROMETHYL)PYRIDINE 2-(trifluoroMethyl)-4-iodopyridine 4-iodo-2-(trifluoromethyl)pyridine 4-IODO-2-(TRIFLUOROMETHYL)PYRIDINE Pyridine,4-iodo-2-(trifluoromethyl)-
CAS	590371-73-6

4-iodo-2-(trifluoromethyl)pyridine - Physico-chemical Properties

Molecular Formula	C6H3F3IN
Molar Mass	272.99
Density	1.974g/ml
Melting Point	24-26 °C
Boling Point	206.2±35.0 °C(Predicted)
pKa	-0.82±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

4-iodo-2-(trifluoromethyl)pyridine - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

4-iodo-2-(trifluoromethyl)pyridine - Introduction

4-iodo-2-(trifluoromethyl)pyridine is an organic compound with the formula C7H4F3IN. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to yellow solid
-Melting point: 98-100 degrees Celsius
-Boiling point: 217-221 degrees Celsius
-Density: 1.94g/cm³
-Solubility: Soluble in common organic solvents (such as ethanol, acetonitrile), insoluble in water

Use:
4-iodo-2-(trifluoromethyl)pyridine is an important organic synthesis intermediate, which is widely used in the fields of medicine, pesticide and material science:
-Drug synthesis: It can be used as a raw material for the synthesis of drugs and bioactive molecules, such as intermediates for anti-tumor drugs.
-pesticide synthesis: in the field of agriculture for synthetic pesticides, fungicides and other pesticides.
-Material science: It can be used to synthesize polymer materials containing pyridine structure, with special optical and electrochemical properties.

Preparation Method:
4-iodo-2-(trifluoromethyl)pyridine can be prepared by the following synthetic route:
1.2-bromo -4-iodine pyridine reacts with trifluoroformic acid to generate 2-bromo -4-iodine -1-trifluoromethyl pyridine.
2. under base catalysis, 2-bromo-4-iodo-1-trifluoromethylpyridine and sodium iodide react to give 4-iodo-2-(trifluoromethyl)pyridine.

Safety Information:
- 4-iodo-2-(trifluoromethyl)pyridine is an organic compound. Pay attention to protective measures during operation and avoid contact with skin and eyes.
-should be operated in a well-ventilated environment, avoid inhalation of its vapor.
-Store the compound properly and avoid contact with flammable substances to prevent fire or explosion.
-During use and storage, please follow the safe handling procedures for chemicals and comply with relevant regulations and legal requirements.

Last Update：2024-04-09 02:00:47