4-phenyl-1,3-thiazole - Names and Identifiers
4-phenyl-1,3-thiazole - Physico-chemical Properties
Molecular Formula | C9H7NS
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Molar Mass | 161.22 |
4-phenyl-1,3-thiazole - Upstream Downstream Industry
4-phenyl-1,3-thiazole - Introduction
4-phenyl-1,3-thiazole is an organic compound with the chemical formula C9H7NS. It has the appearance of a pale yellow solid, is insoluble in water at room temperature, and is soluble in most organic solvents. The following is a detailed description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: 4-phenyl-1,3-thiazole is a pale yellow solid.
-Solubility: It is insoluble in water, but soluble in most organic solvents, such as ethanol, dimethylformamide, etc.
-Melting point: The melting point of this compound is about 88-90°C.
-Molecular structure: The molecular structure of 4-phenyl-1,3-thiazole contains a thiazole ring and a benzene ring, which are connected by a conjugated bond.
Use:
-Chemical reagent: 4-phenyl-1,3-thiazole is often used as a synthetic intermediate for thiazole compounds.
-Fluorescent probe: It has good absorption and emission characteristics for UV light, can be used as a fluorescent probe, and has certain application potential in the fields of analytical chemistry and biology.
-Drug research: 4-phenyl-1,3-thiazole and its derivatives have also received certain attention in drug research, and may have antibacterial and anti-cancer activities.
Method:
- Boronic acid catalytic synthesis: A common preparation method is to use Boronic acid as a catalyst to prepare 4-phenyl-1,3-thiazole through the reaction of thiazole and ozone benzaldehyde.
Safety Information:
-Health hazards: High doses of 4-phenyl-1,3-thiazole are harmful to human health and may cause irritant reactions, such as eye irritation and skin irritation.
-Environmental hazard: The compound is toxic to aquatic organisms, and care should be taken to avoid pollution of water bodies.
-use precautions: in the use of the process should wear appropriate protective equipment, such as gloves, safety glasses. Avoid inhalation or contact with the substance and try to operate in a well-ventilated area. After use, attention should be paid to proper storage and disposal of waste.
Last Update:2024-04-09 02:00:51