4-tert-Butyldimethylsilyloxy-1-iodobutane

4-tert-Butyldimethylsilyloxy-1-iodobutane - Names and Identifiers

Name	tert-butyl(4-iodobutoxy)dimethylsilane
Synonyms	(4-iodobutoxy)dimethyL 1-t-Butyldimethylsilyloxy-4-Iodobutane tert-butyl(4-iodobutoxy)dimethylsilane TERT-BUTYL(4-IODOBUTOXY)DIMETHYLSILANE (4-iodobutoxy)(tert-butyl)dimethylsilane 4-tert-Butyldimethylsilyloxy-1-iodobutane 1-(tert-Butyldimethylsilyloxy)-4-iodobutane SILANE,(1,1-DIMETHYLETHYL)(4-IODOBUTOXY)DIMETHYL- 4-iodo-1-(1,1,2,2-tetramethyl-1-silapropoxy)butane
CAS	92511-12-1
InChI	InChI=1/C10H23IOSi/c1-10(2,3)13(4,5)12-9-7-6-8-11/h6-9H2,1-5H3
InChIKey	INGJYKISFRSCQV-UHFFFAOYSA-N

4-tert-Butyldimethylsilyloxy-1-iodobutane - Physico-chemical Properties

Molecular Formula	C10H23IOSi
Molar Mass	314.28
Density	1.214 g/mL at 25 °C (lit.)
Boling Point	75 °C/0.5 mmHg (lit.)
Flash Point	>230°F
Vapor Presure	0.0297mmHg at 25°C
Specific Gravity	1.214
Storage Condition	2-8℃
Sensitive	7: reacts slowly with moisture/water
Refractive Index	n20/D 1.48(lit.)

4-tert-Butyldimethylsilyloxy-1-iodobutane - Risk and Safety

WGK Germany	3
TSCA	No

4-tert-Butyldimethylsilyloxy-1-iodobutane - Introduction

tert-butyl (4-iodotoxy) dimethylsilane is an organosilicon compound with the formula C9H21IO2Si. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: colorless or light yellow liquid
-Melting Point: Unknown
-Boiling Point: Unknown
-Density: Unknown
-Solubility: Soluble in common organic solvents

Use:
tert-butyl (4-iodotoxy) dimethylsilane are commonly used as reagents and intermediates in organic synthesis, and have the following applications:
-Able to participate in palladium-catalyzed cross-coupling reactions, such as palladium-catalyzed Suzuki reaction, Stille reaction, etc.
-In some chemical reactions can be used as alkyl, carbonyl and alkenyl introduction reagent.

Method:
tert-butyl(4-iodobutoxy)dimethylsilane can be prepared by the following steps:
1. First, tert-butylphenoxydimethylsilane and iodobutane were reacted. Under appropriate conditions, iodobutane will undergo a substitution reaction with tert-butylphenoxydimethylsilane.
2. Finally, through appropriate purification steps, the target product tert-butyl (4-iodotoxy) dimethylsilane was obtained.

Safety Information:
The specific security information dimethylsilane by tert-butyl(4-iodobutoxy) may vary depending on the requirements of different vendors and countries. When using or handling this compound, it is recommended to follow the following safety measures:
-Inhalation, contact with skin or ingestion of the compound may cause a health hazard and strict personal protective measures should be observed.
-Avoid dust, steam, smoke or mist during operation.
-Avoid contact with strong oxidants.
-When storing and using, please follow the safe operation instructions and storage conditions provided by the supplier.

Last Update：2024-04-10 22:29:15