4-trifluoromethoxyphenyl)propan-1-one

4-trifluoromethoxyphenyl)propan-1-one - Names and Identifiers

Name	2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one
Synonyms	4-Trifluoromethoxy isobutyrophenone 4-trifluoromethoxyphenyl)propan-1-one 2-methyl-1-(4-(trifluoromethoxy)propan-1-one 2-methyl-1-(4-trifluoromethoxyphenyl)-1-propanone 2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one 2-methyl-1-(4-(trifluoromethoxy)phenyl)propan-1-one
CAS	56425-84-4
EINECS	260-171-4
InChI	InChI=1/C11H11F3O2/c1-7(2)10(15)8-3-5-9(6-4-8)16-11(12,13)14/h3-7H,1-2H3

4-trifluoromethoxyphenyl)propan-1-one - Physico-chemical Properties

Molecular Formula	C11H11F3O2
Molar Mass	232.2
Density	1.192g/cm³
Melting Point	17℃
Boling Point	247.5°C at 760 mmHg
Flash Point	100.5°C
Vapor Presure	0.0256mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.453

4-trifluoromethoxyphenyl)propan-1-one - Introduction

2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one, also known as 2-methyl -1-[4-(trifluoromethoxy)phenyl] acetone, is an organic compound. The following is an introduction to its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless liquid or solid
-Molecular formula: C11H11F3O2
-Molecular weight: 238.2g/mol
-Melting point: 35-40°C
-Boiling Point: 80-85°C(0.5 mmHg)

Use:
2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one has certain applications in organic synthetic chemistry:
-As a chemical intermediate: It can be used to synthesize other organic compounds, such as drugs, dyes, pesticides, etc.
-As a research tool: 2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one can be used as a marker for drug metabolism research.

Preparation Method:
2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one can be synthesized by the following steps:
1. p-aminobenzoic acid ester is reacted with trifluoromethyl ether to obtain p-aminophenyl trifluorocresol.
2. p-Aminophenyl trifluorocresol reacts with isobutyl ketone to give 2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one.

Safety Information:
2-Methyl-1[4-(trifluoromethoxy)phenyl]propan-1-one it is a relatively safe compound under general conditions, the following matters still need to be paid attention:
-Avoid contact with skin, eyes and respiratory tract. Wear protective gloves, goggles and a protective mask when handling.
-Use in a well-ventilated place to avoid inhaling its vapors.
-Store in a closed container, away from fire and oxidizing agents.
-Detailed safety information can be obtained from the Safety Data Sheet (SDS) of the relevant chemical.

Last Update：2024-04-09 19:05:50