4-氨基-6-氯-5-甲氧基嘧啶

4-氨基-6-氯-5-甲氧基嘧啶 - Names and Identifiers

Name	4-Amino-6-Chloro-5-Methoxypyrimidine
Synonyms	6-CHLORO-5-METHOXYPYRIMIDIN-4-AMINE 6-chloro-5-methoxypyrimidin-4-amine 6-Chloro-5-methoxy-4-pyrimidinamine 4-Amino-6-Chloro-5-Methoxypyrimidine 4-Amino-6-Chloro-5-Methoxy Pyrimidin 4-AMINO-6-CHLORO-5-METHOXYPYRIMIDINE 4-Pyrimidinamine, 6-chloro-5-methoxy- 6-Chloro-5-MethoxypyriMidin-4-ylaMine 4-(p-Aminobenzene Sulfonamino)-5Methoxy-6-Chloro Pyrimidine) 4-(p-AMinobenzene SulfonaMino)-5Methoxy-6-Chloro PyriMidine)
CAS	5018-41-7
EINECS	225-700-5
InChI	InChI=1/C5H6ClN3O/c1-10-3-4(6)8-2-9-5(3)7/h2H,1H3,(H2,7,8,9)

4-氨基-6-氯-5-甲氧基嘧啶 - Physico-chemical Properties

Molecular Formula	C5H6ClN3O
Molar Mass	159.57
Density	1.398±0.06 g/cm3(Predicted)
Melting Point	176-178 °C
Boling Point	305.4±37.0 °C(Predicted)
Flash Point	138.5°C
Vapor Presure	0.000822mmHg at 25°C
pKa	1.51±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.585
Physical and Chemical Properties	White powder.

4-氨基-6-氯-5-甲氧基嘧啶 - Introduction

It is an organic compound with the chemical formula C5H6ClN3O. The following is its nature, use, preparation and safety information:

Nature:
-Appearance: colorless or light yellow crystal
-Melting point: 139-141 degrees Celsius
-Solubility: Soluble in ethanol, ether and chloroform, slightly soluble in water
-Stability: relatively stable at room temperature, avoid contact with strong oxidants and strong acids

Use:
-Chemical synthesis: widely used in organic synthesis reactions, such as as intermediates for the preparation of heterocyclic compounds, pharmaceuticals and pesticides
-Drug research: used as drug raw materials in drug research, especially for the development of anti-cancer drugs
-Agriculture: In the agricultural field, it can be used to prepare some pesticides such as pesticides and herbicides

Preparation Method:
It can be prepared by the following methods:
-first, starting with a reactant containing 4-aminopyrimidine;
-Then, under the appropriate reaction conditions, use monochlorinated or trichlorinated hydrogen chloride and methanol to react to produce a phosphonium.

Safety Information:
-It is relatively safe under correct use, but the following matters still need to be paid attention:
-Wear appropriate personal protective equipment such as protective gloves, goggles and protective clothing during operation;
-Avoid inhaling dust, contact with skin and mouth;
-Avoid contact with chemicals such as strong oxidants and strong acids to avoid dangerous reactions;
-If exposed or inhaled, rinse immediately with plenty of water and seek medical help.

Please note that before using any chemical, please make sure to understand its nature, characteristics and safe operation requirements, and take necessary safety measures to operate.

Last Update：2024-04-09 21:01:54