4-氨基甲酰苯硼酸
[4-(Aminocarbonyl)phenyl]-boronic acid
CAS: 123088-59-5
Molecular Formula: C7H8BNO3
4-氨基甲酰苯硼酸 - Names and Identifiers
4-氨基甲酰苯硼酸 - Physico-chemical Properties
| Molecular Formula | C7H8BNO3 |
| Molar Mass | 164.95 |
| Density | 1.32±0.1 g/cm3(Predicted) |
| Melting Point | 242-252°C |
| Boling Point | 414.3±47.0 °C(Predicted) |
| Flash Point | 204.4°C |
| Vapor Presure | 1.32E-07mmHg at 25°C |
| Appearance | powder or crystals |
| Color | white to off-white |
| pKa | 7.87±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.585 |
4-氨基甲酰苯硼酸 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| TSCA | No |
| HS Code | 29310095 |
| Hazard Note | Corrosive |
| Hazard Class | IRRITANT |
4-氨基甲酰苯硼酸 - Introduction
4-Carbamylphenylboronic acid is an organoborate compound with the chemical formula C8H9BNO3. The following is a description of the nature, use, preparation and safety information of 4-carbamylphenylboronic acid:
Nature:
-Appearance: 4-carbamylphenylboronic acid exists in the form of white crystals.
-Solubility: It is soluble in water and some organic solvents, such as ethanol, ether and chloroform.
-Melting point: between about 128-130°C.
- pH: Its aqueous solution is acidic.
Use:
-Catalyst: 4-Carbamylphenylboronic acid can be used as a catalyst for metal-organic chemical reactions, such as C- C bond formation reactions and C- H activation reactions.
-Fluorescent probe: It can also be used as a fluorescent probe for biomedical research, such as cell imaging and analysis.
Preparation Method:
There are several methods for preparing 4-carbamylphenylboronic acid. One of the common methods is to react 4-aminobenzoic acid and boric acid in an alcohol solvent. After a period of reaction, the product can be obtained by crystallization or concentration of the solution.
Safety Information:
When using 4-carbamylphenylboronic acid, you need to pay attention to the following safety matters:
-It is an organic compound and care should be taken to avoid skin contact, inhalation or ingestion.
-Use appropriate personal protective equipment such as lab gloves, goggles, and lab coats when handling.
-Waste should be disposed of in accordance with local regulations and should not be discharged into water sources or the environment.
Remember to follow laboratory safety practices when using or handling 4-carbamylphenylboronic acid and refer to the relevant safety data form for this compound.
Nature:
-Appearance: 4-carbamylphenylboronic acid exists in the form of white crystals.
-Solubility: It is soluble in water and some organic solvents, such as ethanol, ether and chloroform.
-Melting point: between about 128-130°C.
- pH: Its aqueous solution is acidic.
Use:
-Catalyst: 4-Carbamylphenylboronic acid can be used as a catalyst for metal-organic chemical reactions, such as C- C bond formation reactions and C- H activation reactions.
-Fluorescent probe: It can also be used as a fluorescent probe for biomedical research, such as cell imaging and analysis.
Preparation Method:
There are several methods for preparing 4-carbamylphenylboronic acid. One of the common methods is to react 4-aminobenzoic acid and boric acid in an alcohol solvent. After a period of reaction, the product can be obtained by crystallization or concentration of the solution.
Safety Information:
When using 4-carbamylphenylboronic acid, you need to pay attention to the following safety matters:
-It is an organic compound and care should be taken to avoid skin contact, inhalation or ingestion.
-Use appropriate personal protective equipment such as lab gloves, goggles, and lab coats when handling.
-Waste should be disposed of in accordance with local regulations and should not be discharged into water sources or the environment.
Remember to follow laboratory safety practices when using or handling 4-carbamylphenylboronic acid and refer to the relevant safety data form for this compound.
Last Update：2024-04-10 22:29:15
