4-氯-5-氟嘧啶
4-Chloro-5-fluoropyrimidine
CAS: 347418-42-2
Molecular Formula: C4H2ClFN2
4-氯-5-氟嘧啶 - Names and Identifiers
| Name | 4-Chloro-5-fluoropyrimidine |
| Synonyms | 4-Chloro-5-fluoropyrimidine 4-Chloro-5-fluoro-1,3-diazine PyriMidine,4-chloro-5-fluoro- Pyrimidine, 4-chloro-5-fluoro- Pyrimidine, 4-chloro-5-fluoro- (9CI) |
| CAS | 347418-42-2 |
| InChI | InChI=1/C4H2ClFN2/c5-4-3(6)1-7-2-8-4/h1-2H |
4-氯-5-氟嘧啶 - Physico-chemical Properties
| Molecular Formula | C4H2ClFN2 |
| Molar Mass | 132.52 |
| Density | 1.439±0.06 g/cm3(Predicted) |
| Boling Point | 181.1±20.0 °C(Predicted) |
| Flash Point | 63.3°C |
| Vapor Presure | 1.18mmHg at 25°C |
| pKa | -1.11±0.16(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.505 |
4-氯-5-氟嘧啶 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| UN IDs | 1993 |
| HS Code | 29335990 |
| Hazard Class | 3 |
| Packing Group | Ⅲ |
4-氯-5-氟嘧啶 - Introduction
It is an organic compound with the chemical formula C4H2ClFN2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White to light yellow crystalline solid.
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide and dimethylformamide, but its solubility in water is relatively low.
-Melting point: Its melting point is about 50-52 ℃.
Use:
-is an important intermediate compound, which can be used to synthesize other organic compounds, such as pharmaceuticals, dyes and pesticides.
-In the field of medicine, it is often used as an intermediate in the synthesis of drugs, such as the synthesis of anti-tumor drugs or other therapeutic agents.
-It can also be used as a synthetic starting material for dyes and pesticides.
Preparation Method:
-m can be prepared by substitution reaction or carboxylation reaction. A common method is obtained by reacting 2,3-dimethoxypyridine with sodium trifluoroacetate, followed by chlorination.
Safety Information:
-Generally, it is relatively safe under normal use conditions, but it is still necessary to comply with relevant safety operating regulations.
-Because it is a chemical substance, contact with the skin, eyes or inhalation of its vapors may cause irritation, so it is necessary to wear appropriate protective equipment when using, such as gloves, safety glasses and respiratory protection.
-During storage and handling, avoid contact with oxidants, strong acids or alkalis to prevent dangerous reactions.
-If ingested or exposed, seek medical attention immediately and bring packaging or chemical safety data sheets for proper handling.
Nature:
-Appearance: White to light yellow crystalline solid.
-Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide and dimethylformamide, but its solubility in water is relatively low.
-Melting point: Its melting point is about 50-52 ℃.
Use:
-is an important intermediate compound, which can be used to synthesize other organic compounds, such as pharmaceuticals, dyes and pesticides.
-In the field of medicine, it is often used as an intermediate in the synthesis of drugs, such as the synthesis of anti-tumor drugs or other therapeutic agents.
-It can also be used as a synthetic starting material for dyes and pesticides.
Preparation Method:
-m can be prepared by substitution reaction or carboxylation reaction. A common method is obtained by reacting 2,3-dimethoxypyridine with sodium trifluoroacetate, followed by chlorination.
Safety Information:
-Generally, it is relatively safe under normal use conditions, but it is still necessary to comply with relevant safety operating regulations.
-Because it is a chemical substance, contact with the skin, eyes or inhalation of its vapors may cause irritation, so it is necessary to wear appropriate protective equipment when using, such as gloves, safety glasses and respiratory protection.
-During storage and handling, avoid contact with oxidants, strong acids or alkalis to prevent dangerous reactions.
-If ingested or exposed, seek medical attention immediately and bring packaging or chemical safety data sheets for proper handling.
Last Update：2024-04-09 20:44:15
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Product Name: 4-Chloro-5-fluoropyrimidine Visit Supplier Webpage Request for quotationCAS: 347418-42-2
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-chloro-5-fluoropyrimidine Visit Supplier Webpage Request for quotationCAS: 347418-42-2
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Pyrimidine, 4-chloro-5-fluoro- (9CI) Visit Supplier Webpage Request for quotation
CAS: 347418-42-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 347418-42-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
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