4-甲基-1-(苯基甲基)-3-哌啶酮

4-甲基-1-(苯基甲基)-3-哌啶酮 - Names and Identifiers

Name	1-benzyl-4-methylpiperidin-3-one
Synonyms	Tofacitinib Impurity 192 1-benzyl-4-methylpiperidin-3-on 1-benzyl-4-methylpiperidin-3-one Methyl-1-(phenylmethyl) 3-piperidone 4-Methyl-1-(phenylmethyl)-3-piperidinone 4-Methyl-1-(Phenylmethyl)-3-Piperidinone 3-Piperidinone, 4-Methyl-1-(phenylMethyl)- Methyl-1-(phenylMethyl) 3-piperidone hydrochloride
CAS	32018-96-5
EINECS	1312995-182-4
InChI	InChI=1/C13H17NO/c1-11-7-8-14(10-13(11)15)9-12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3

4-甲基-1-(苯基甲基)-3-哌啶酮 - Physico-chemical Properties

Molecular Formula	C13H17NO
Molar Mass	203.28
Density	1.057
Boling Point	302.9±35.0 °C(Predicted)
Flash Point	128.085°C
Vapor Presure	0.001mmHg at 25°C
pKa	6.13±0.40(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C
Refractive Index	1.543

4-甲基-1-(苯基甲基)-3-哌啶酮 - Introduction

It is also known as 1-phenylmethyl-4-methylpiperidin-3-one, and is an organic compound. Its molecular formula is C15H19NO and its relative molecular mass is 233.32g/mol.

Nature:
is a white or yellowish crystalline solid. It has a special aroma. Stable at room temperature, soluble in many organic solvents, such as ethers, alcohols and hydrocarbons.

Use:
It has a variety of applications in the pharmaceutical and chemical industries. It is often used as an intermediate in organic synthesis and can be used to synthesize various drugs and compounds. At the same time, it is also used as a solvent and surfactant in the chemical industry.

Method:
There are many preparation methods. A commonly used synthetic method is the reaction of 1-piperidinecarboxylic acid with methylacetophenone under basic conditions to produce the target product via a carbonyl reaction.

Safety Information:
It is generally safe under reasonable conditions of use. However, it is an organic compound, which is corrosive and irritating. Wear appropriate personal protective equipment, such as gloves and glasses, and avoid contact with skin and eyes when using or handling. Inhalation or ingestion may lead to poisoning, special attention should be paid to safe operation.

Last Update：2024-04-09 21:11:58