4-甲基-2-(4-吡啶基)噻唑-5-羧酸

4-甲基-2-(4-吡啶基)噻唑-5-羧酸 - Names and Identifiers

Name	4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid
Synonyms	4-Methyl-2-(4-pyridyl)thiazole-5-carboxylic acid 4-methyl-2-(4-pyridyl)-5-thiazolecarboxylic acid 2-(4-Pyridyl)-4-methylthiazole-5-carboxylic acid 2-(4-Pyridyl)-4-methylthiazole-5-carboxylic acid 4-Methyl-2-pyridin-4-ylthiazole-5-carboxylic acid 4-Methyl-2-(4-pyridinyl)-5-thiazolecarboxylic acid 4-methyl-2-pyrid-4-yl-1,3-thiazole-5-carboxylic acid 5-Thiazolecarboxylic acid, 4-Methyl-2-(4-pyridinyl)- 4-Methyl-2-pyridin-4-yl-1,3-thiazole-5-carboxylic acid
CAS	144060-98-0
InChI	InChI=1/C10H8N2O2S/c1-6-8(10(13)14)15-9(12-6)7-2-4-11-5-3-7/h2-5H,1H3,(H,13,14)

4-甲基-2-(4-吡啶基)噻唑-5-羧酸 - Physico-chemical Properties

Molecular Formula	C10H8N2O2S
Molar Mass	220.25
Density	1.381
Melting Point	290-313 °C
Boling Point	467℃
Flash Point	236℃
Vapor Presure	1.6E-09mmHg at 25°C
pKa	1.71±0.37(Predicted)
Storage Condition	2-8°C
Refractive Index	1.636

4-甲基-2-(4-吡啶基)噻唑-5-羧酸 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust.
WGK Germany	3
Hazard Note	Harmful
Hazard Class	IRRITANT

4-甲基-2-(4-吡啶基)噻唑-5-羧酸 - Introduction

4-methyll-2-pyrid-4-yl-1, 3-thiazole-5-carboxylic acid is an organic compound with the chemical formula C12H10N2O2S. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 4-methyll-2-pyrid-4-yl-1, 3-thiazole-5-carboxylic acid is a white crystalline solid.
-Solubility: It has low solubility in water, but it dissolves better in organic solvents.

Use:
-Chemical industry: 4-methyll-2-pyrid-4-yl-1, 3-thiazole-5-carboxylic acid is an important intermediate that can be used to synthesize other organic compounds.
-Drug: This compound has potential pharmaceutical activity, so it may be used in drug development.

Method:
-4-methyll-2-pyrid-4-yl-1, 3-thiazole-5-carbolic acid has a variety of preparation methods, one of which is commonly used to synthesize by hydrogenation reduction reaction. The specific steps include the reaction of the corresponding ketone compound with sulfuric acid carbamate, then, a hydrogenation reduction reaction is performed to obtain the target product.

Safety Information:
The safety of -4-methyll-2-pyrid-4-yl-1, 3-thiazole-5-carboxylic acid has not been fully evaluated. Please take appropriate safety measures during laboratory operation. Contact with skin, eyes and inhalation should be avoided. Wash with water and soap after surgery. In case of accidental contact, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:52