40003-41-6

40003-41-6 - Names and Identifiers

Name	2-bromo-4-methyl-1,3-thiazole-5-carboxylic acid
Synonyms	IFLAB-BB F2124-0223 2-BroMo-4-Methyl-5-thiazolecarboxylic acid 2-bromo-4-methylthiazole-5-carboxylic acid 2-BROMO-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID 5-Thiazolecarboxylic acid, 2-bromo-4-methyl- 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID 2-bromo-4-methyl-1,3-thiazole-5-carboxylic acid
CAS	40003-41-6
InChI	InChI=1/C5H4BrNO2S/c1-2-3(4(8)9)10-5(6)7-2/h1H3,(H,8,9)

40003-41-6 - Physico-chemical Properties

Molecular Formula	C5H4BrNO2S
Molar Mass	222.06
Density	1.895±0.06 g/cm3(Predicted)
Melting Point	158 °C (dec.)
Boling Point	349.5±22.0 °C(Predicted)
Flash Point	165.2°C
Vapor Presure	1.75E-05mmHg at 25°C
pKa	2.16±0.37(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.639

40003-41-6 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	43 - May cause sensitization by skin contact
Safety Description	36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3

40003-41-6 - Introduction

2-bromo-4-methyl-1,3-thiazole-5-carboxylic acid is an organic compound with the chemical formula C6H5BrNO2S. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White solid
-melting point: 126-128 ℃
-Soluble: Soluble in ethanol, benzene and dichloromethane

Use:
2-bromo-4-methyl-1,3-thiazole-5-carboxylic acid can be used as a chemical reagent and is widely used in organic synthesis reactions. It can be used for the synthesis of compounds with biological activity, and for the preparation of pharmaceutical and pesticide intermediates. In addition, it can also be used to synthesize agricultural chemicals and dyes.

Preparation Method:
The preparation of 2-bromo-4-methyl-1,3-thiazole-5-carboxylic acid is usually carried out by the following steps:
1. At a certain temperature, 2-bromo -4-methyl thiazole and calcium carbonate are esterified with acetic acid to generate the corresponding esterification product.
2. acylation of the esterification product with sulfuryl chloride to obtain 2-bromo-4-methyl-1, 3-thiazole-5-carbonic acid.

Safety Information:
2-bromo-4-methyl-1,3-thiazole-5-carboxylic acid has limited safety information. It may cause irritation to the eyes, skin and respiratory tract. Wear appropriate personal protective equipment and avoid contact with skin and eyes. When used in laboratory and industrial environments, relevant safety practices need to be observed.

Last Update：2024-04-09 20:52:54