401620-74-4 - Names and Identifiers
Name | 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
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Synonyms | fmoc-D-2-cyanophenylalanine Fmoc-D-2-Cyanophenylalanine Fmoc-2-Cyano-D-phenylalanine (R)-Fmoc-2-amino-(2-cyanophenyl)propanoic acid (9H-Fluoren-9-yl)MethOxy]Carbonyl D-2-Cyanophe 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine 2-Cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine 2-Cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine L-phenylalanine, 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- D-Phenylalanine, 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(2-cyanophenyl)propanoic acid (2S)-3-(2-Cyanophenyl)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (2R)-3-(2-cyanophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
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CAS | 401620-74-4
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InChI | InChI=1/C25H20N2O4/c26-14-17-8-2-1-7-16(17)13-23(24(28)29)27-25(30)31-15-22-20-11-5-3-9-18(20)19-10-4-6-12-21(19)22/h1-12,22-23H,13,15H2,(H,27,30)(H,28,29)/t23-/m0/s1 |
401620-74-4 - Physico-chemical Properties
Molecular Formula | C25H20N2O4
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Molar Mass | 412.44 |
Density | 1.35g/cm3 |
Boling Point | 666°C at 760 mmHg |
Flash Point | 356.6°C |
Vapor Presure | 1.2E-18mmHg at 25°C |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.672 |
401620-74-4 - Risk and Safety
401620-74-4 - Introduction
2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is an organic compound with the chemical formula C30H23N3O4. It is a cyano protecting reagent containing D-2-cyanophenylalanine.
2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is commonly used in solid-phase synthesis as a protective reagent for amino acids. It protects the reactive groups in the amino acid by adding a protecting group Fmoc on the side chain of the amino acid to prevent uncontrolled reactions during the reaction. This ensures that the desired chemical reaction takes place only at the specified site.
The method of preparing 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is similar to general amino acid synthesis. Usually, starting from L-phenylalanine, the 2-cyano group is introduced by chemical reaction, and then the side chain of the amino acid is protected with Fmoc. The specific synthesis method requires the specific operation of the organic chemistry laboratory.
Regarding safety information, since 2-cyano-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine is an organic compound, you need to pay attention to protective measures when using it. Contact with eyes, skin or inhalation may be harmful to health. Therefore, appropriate personal protective equipment should be worn during operation, such as laboratory gloves and eye protection glasses. At the same time, attention should be paid to operating in a well-ventilated place to avoid inhaling harmful vapors.
Last Update:2024-04-10 22:29:15